LDB3 Antibodies

AND LDB3 ELISA kits, LDB3 Proteins

Many biological assays use antibodies to detect LDB3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LDB3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LDB3 antibodies...

We validate the specificity of these antibodies to LDB3 by testing them on tissues known to express LDB3 positively and negatively. Browse below to find the LDB3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LDB3 Infographic by Boster Bio

All LDB3 Products

Product

Figures

Specificity

Applications

Price

Anti-LIM domain-binding protein 3 LDB3 Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A04633
100ul

LDB3 (NM_001080115) Human Recombinant Protein

$1249
Cat # PROTO75112
20 µg

LDB3 (NM_001080115) Human Over-expression Lysate

Human

$628
Cat # LS011155
100 µg

LDB3 Overview

Facts about LIM domain-binding protein 3.

LDB3 3D structure. Source: alphafold

LIM domain-binding protein 3 (LDB3)

May function as an adapter in striated muscle to couple protein kinase C-mediated signaling via its LIM domains to the cytoskeleton. .

Gene Information

Human
Gene Name:	LDB3
Uniprot:	O75112
Entrez:	11155

Family

Belongs to:

No superfamily

Alternative Names

CMD1C; CYPHER; KIAA01613; KIAA0613FLJ35865; LDB3Z1; LDB3Z4; LIM domain binding 3; LIM domain-binding protein 3; ORACLE; PDLIM6; PDZ and LIM domain 6; Protein cypher; ZASPLVNC3; Z-band alternatively spliced PDZ-motif protein

Molecular Weight

Mass (kDA):
77.135 kDA

Genomic Context


Human

Location:	10q23.2
Sequence:	10; NC_000010.11 (86666788..86736072)

Tissue Specificity

Expressed primarily in skeletal muscle and to a lesser extent in heart. Also detected in brain and placenta.

Subcellular Localizations

Cytoplasm, perinuclear region. Cell projection, pseudopodium. Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line. Localized to the cytoplasm around nuclei and pseudopodia of undifferentiated cells and detected throughout the myotubes of differentiated cells. Colocalizes with ACTN2 at the Z-lines.

Diseases

Cardiomyopathies
Myopathy
Cardiomyopathy, Dilated
Weakness
Cardiomyopathy, Familial Idiopathic
Heart Failure
Hypertrophy
Dystrophy
Muscle Weakness
3-methylglutaconic Aciduria Type 2
Ventricular Dysfunction, Left
Cardiac Arrhythmia

Hypertrophic Cardiomyopathy
Muscular Dystrophy
Neuromuscular Diseases
Myotonic Dystrophy
Sudden Cardiac Death
Peripheral Neuropathy

Pathways

Pathogenesis
Localization
Cardiac Conduction
Mrna Splicing
Gastrulation
Autophagic Cell Death
Mitosis
Gluconeogenesis
Cell-matrix Adhesion
Metaphase
Ion Homeostasis
Sarcomerogenesis
Organ Development

Translation
Cell Death
Mrna Processing
Apoptotic Nuclear Changes
Rna Interference
Stress Fiber Assembly
Glycolysis

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LDB3

References

PMID: 10427098 by Faulkner G., et al. ZASP: a new Z-band alternatively spliced PDZ-motif protein.

PMID: 11842093 by Frey N., et al. Calsarcin-3, a novel skeletal muscle-specific member of the calsarcin family, interacts with multiple Z-disc proteins.