LDB1 Antibodies

AND LDB1 ELISA kits, LDB1 Proteins

Many biological assays use antibodies to detect LDB1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LDB1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LDB1 antibodies...

We validate the specificity of these antibodies to LDB1 by testing them on tissues known to express LDB1 positively and negatively. Browse below to find the LDB1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LDB1 Infographic by Boster Bio

All LDB1 Products

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Specificity

Applications

Price

Anti-LIM domain-binding protein 1 LDB1 Antibody

3 Q&As

Human

ELISA, WB

$629
Cat # A01977
100ug

LDB1 (NM_003893) Human Over-expression Lysate

Human

$628
Cat # LS008861
100 µg

LDB1 Overview

Facts about LIM domain-binding protein 1.

LDB1 3D structure. Source: alphafold

LIM domain-binding protein 1 (LDB1)

Binds to the LIM domain of a huge variety of LIM domain- containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions.

Plays a role in the growth of interneurons and motor neurons in cooperation with LHX3 and ISL1. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression.

Gene Information

Human
Gene Name:	LDB1
Uniprot:	Q86U70
Entrez:	8861

Family

Belongs to:

LDB family

Alternative Names

carboxy terminal LIM domain protein 2; Carboxyl-terminal LIM domain-binding protein 2; CLIM-2; CLIM2hLdb1; LDB-1; LIM domain binding 1; LIM domain-binding factor-1; LIM domain-binding protein 1; NLILIM domain-binding factor CLIM2; Nuclear LIM interactor

Molecular Weight

Mass (kDA):
46.533 kDA

Genomic Context


Human

Location:	10q24.32
Sequence:	10; NC_000010.11 (102102100..102120368, complement)

Tissue Specificity

Expressed in a wide range of adult tissues including brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, lung and peripheral blood leukocytes.

Subcellular Localizations

Nucleus.

Diseases

Leukemia
Neoplasms
Malignant Neoplasms
Cell Transformation, Neoplastic
Malignant Neoplasm Of Breast
Pituitary Diseases
Carcinoma
Mammary Neoplasms
Precursor T-cell Lymphoblastic Leukemia-lymphoma
Leukemia, T-cell
Acute Erythroblastic Leukemia
Acute Lymphocytic Leukemia
Chromosomal Translocation

Nervousness
Nail-patella Syndrome
Malignant Paraganglionic Neoplasm
Acute Leukemia
Adult T-cell Lymphoma/leukemia
Tissue Adhesions
Dysplasia

Interacting Proteins

IDI2
LHX4
LHX6
LHX8
LMO1

LMO2
LMO4
SSBP3
SSBP4

Pathways

Cell Differentiation
Oncogenesis
Localization
Cell Proliferation
Pathogenesis
Head Development
Limb Development
Stem Cell Maintenance
Cell Fate Determination
Regulation Of Gene Expression
Gastrulation
Cell Development
Developmental Process

Limb Bud Formation
Neurogenesis
Cell Fate Specification
Translation
Megakaryocyte Development
Cell Adhesion
Cell Activation

PTMs

Phosphorylation
Acetylation

Ubiquitination
Glycosylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LDB1

References

PMID: 9799849 by Semina E.V., et al. Cloning and chromosomal localization of two novel human genes encoding LIM-domain binding factors CLIM1 and CLIM2/LDB1/NLI.

PMID: 10640831 by Drechsler M., et al. Genomic structure, alternative transcripts and chromosome location of the human LIM domain binding protein gene LDB1.