LCE3B Antibodies

AND LCE3B ELISA kits, LCE3B Proteins

Many biological assays use antibodies to detect LCE3B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LCE3B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LCE3B antibodies...

We validate the specificity of these antibodies to LCE3B by testing them on tissues known to express LCE3B positively and negatively. Browse below to find the LCE3B antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LCE3B Infographic by Boster Bio

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LCE3B (NM_178433) Human Over-expression Lysate

Human

$628
Cat # LS353143
100 µg

LCE3B Overview

Facts about Late cornified envelope protein 3B.

LCE3B 3D structure. Source: alphafold

Late cornified envelope protein 3B (LCE3B)

A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species.

Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens (PubMed:28634035). .

Gene Information

Human
Gene Name:	LCE3B
Uniprot:	Q5TA77
Entrez:	353143

Family

Belongs to:

LCE family

Alternative Names

Late cornified envelope protein 3B

Molecular Weight

Mass (kDA):
9.812 kDA

Genomic Context


Human

Location:	1q21.3
Sequence:	1; NC_000001.11 (152613811..152614098)

Tissue Specificity

Skin-specific. Expression was readily detected in adult trunk skin, adult arm skin, fetal skin, penal skin, vulva, esophagus and tongue. Not expressed in the cervix, rectum, lung, colon, or placenta.

Interacting Proteins

CYSRT1
KRTAP10-9
KRTAP5-9
KRTAP9-2
KRTAP9-3

LCE1B
LCE1D
LCE1E
LCE1F
LCE2C

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LCE3B

References

PMID: 15854049 by Jackson B., et al. Late cornified envelope family in differentiating epithelia -- response to calcium and ultraviolet irradiation.

PMID: 28634035 by Niehues H., et al. Psoriasis-Associated Late Cornified Envelope (LCE) Proteins Have Antibacterial Activity.