La-related protein 6 Antibodies

AND LARP6 ELISA kits, La-related protein 6 Proteins

Many biological assays use antibodies to detect La-related protein 6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with La-related protein 6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop La-related protein 6 antibodies...

We validate the specificity of these antibodies to La-related protein 6 by testing them on tissues known to express LARP6 positively and negatively. Browse below to find the LARP6 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LARP6 Infographic by Boster Bio

All LARP6 Products

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Specificity

Applications

Price

LARP6 (NM_197958) Human Recombinant Protein

$813
Cat # PROTQ9BRS8
20 µg

LARP6 (NM_197958) Human Over-expression Lysate

Human

$628
Cat # LS055323
100 µg

LARP6 Overview

Facts about La-related protein 6.

LARP6 3D structure. Source: alphafold

La-related protein 6 (LARP6)

Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5' UTR.

This law requires VIM and MYH10 filaments, and the helicase DHX9. .

Gene Information

Human
Gene Name:	LARP6
Uniprot:	Q9BRS8
Entrez:	55323

Family

Belongs to:

No superfamily

Alternative Names

Acheron; Achn; death-associated LA motif protein; FLJ11196; La ribonucleoprotein domain family member 6; La ribonucleoprotein domain family, member 6; la-related protein 6

Molecular Weight

Mass (kDA):
54.737 kDA

Genomic Context


Human

Location:	15q23
Sequence:	15; NC_000015.10 (70829130..70854157, complement)

Tissue Specificity

Expressed in numerous tissues.

Subcellular Localizations

Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm.

Diseases

Fibrosis
Insulin Resistance
Diabetes Mellitus, Non-insulin-dependent
Tumor Angiogenesis
Coronary Heart Disease
Obesity
Hypoxia
Hepatic Fibrosis

Coronary Artery Disease
Diabetes Mellitus

Pathways

Translation
Glucose Homeostasis
Tissue Development
Cell Cycle
Response To Hypoxia
Dna Repair
Insulin Processing
Protein Secretion
Angiogenesis

Regulation Of Translation
Pathogenesis
Secretion

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LARP6

References

PMID: 17383118 by Valavanis C., et al. Acheron, a novel member of the Lupus antigen family, is induced during the programmed cell death of skeletal muscles in the moth Manduca sexta.

PMID: 20603131 by Cai L., et al. Nonmuscle myosin-dependent synthesis of type I collagen.