LanC-like protein 2 Antibodies

AND LANCL2 ELISA kits, LanC-like protein 2 Proteins

Many biological assays use antibodies to detect LanC-like protein 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LanC-like protein 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LanC-like protein 2 antibodies...

We validate the specificity of these antibodies to LanC-like protein 2 by testing them on tissues known to express LANCL2 positively and negatively. Browse below to find the LANCL2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LANCL2 Infographic by Boster Bio

All LANCL2 Products

Product

Figures

Specificity

Applications

Price

Anti-LanC-like protein 2 LANCL2 Antibody

Human, Mouse, Rat

ELISA, IHC-P, WB

$449
Cat # A07373
0.1 mg

LANCL2 (NM_018697) Human Recombinant Protein

$1249
Cat # PROTQ9NS86
20 µg

Anti-LANCL2 Mouse Monoclonal Antibody [Clone ID: OTI2A11]

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$523
Cat # M07373
100 µl

LANCL2 (NM_018697) Human Over-expression Lysate

Human

$628
Cat # LS055915
100 µg

LANCL2 Overview

Facts about LanC-like protein 2.

LANCL2 3D structure. Source: alphafold

LanC-like protein 2 (LANCL2)

Necessary for abscisic acid (ABA) binding to the cell membrane and activation of the ABA signaling pathway in granulocytes. .

Gene Information

Human
Gene Name:	LANCL2
Uniprot:	Q9NS86
Entrez:	55915

Family

Belongs to:

LanC-like protein family

Alternative Names

G protein-coupled receptor 69B; GPR69B; LanC (bacterial lantibiotic synthetase component C)-like 2; LanC lantibiotic synthetase component C-like 2 (bacterial); lanC-like protein 2; TASPMGC87139; Testis-specific adriamycin sensitivity protein

Molecular Weight

Mass (kDA):
50.854 kDA

Genomic Context


Human

Location:	7p11.2
Sequence:	7; NC_000007.14 (55365448..55433742)

Tissue Specificity

Expressed in brain and testis.

Subcellular Localizations

Nucleus. Cytoplasm. Cell membrane. Localizes to the juxta-nuclear vesicles (PubMed:16979580). Associates with the cortical actin cytoskeleton (PubMed:16979580). Cholesterol depletion by methyl-beta-cyclodextrin causes partial dissociation from the cell membrane in vitro and an enhanced cell detachment from the matrix in vivo (PubMed:16979580). Membrane-association is important for the increased cellular sensitivity to an anticancer drug (adriamycin) (PubMed:16979580).

Diseases

Insulinoma
Inflammation
Diabetes Mellitus
Sarcoma
Innate Immune Response
Malignant Squamous Cell Neoplasm
Dermatitis
Metaplasia
Inflammatory Bowel Diseases
Glioblastoma
Lung Diseases
Uterine Neoplasms
Inflammatory Response

Carcinoma
Diabetes Mellitus, Non-insulin-dependent
Malignant Neoplasms
Neoplasms
Silicosis
Nervousness
Mammary Neoplasms

Interacting Proteins

APPBP2
TERF2IP

Pathways

Sensitization
Phagocytosis
Transsulfuration
Cell Migration
Chemotaxis
Paracrine Signaling
Response To Uv-b
Innate Immune Response
Immune Response

Localization
Macrophage Activation
Inflammatory Response

PTMs

Myristoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LANCL2

References

PMID: 11762191 by Mayer H., et al. Molecular cloning, characterization, and tissue-specific expression of human LANCL2, a novel member of the LanC-like protein family.

PMID: 16979580 by Landlinger C., et al. Myristoylation of human LanC-like protein 2 (LANCL2) is essential for the interaction with the plasma membrane and the increase in cellular sensitivity to adriamycin.