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- Table of Contents
Facts about Laminin subunit gamma-2.
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Human | |
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Gene Name: | LAMC2 |
Uniprot: | Q13753 |
Entrez: | 3918 |
Belongs to: |
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No superfamily |
BM600; BM600-100kDa; Cell-scattering factor 140 kDa subunit; CSF 140 kDa subunit; CSF; EBR2; EBR2A; Epiligrin subunit gamma; kalinin (105kD); Kalinin subunit gamma; Kalinin/nicein/epiligrin 100 kDa subunit; kalinin-105kDa; ladsin (140kDa); Ladsin 140 kDa subunit; LAMB2Tlaminin, gamma 2 (nicein (100kD), kalinin (105kD), BM600 (100kD), Herlitzjunctional epidermolysis bullosa)); Laminin B2t chain; laminin subunit gamma-2; laminin, gamma 2; Laminin-5 subunit gamma; LAMNB2B2T; Large adhesive scatter factor 140 kDa subunit; MGC138491; MGC141938; nicein (100kDa); Nicein subunit gamma; nicein-100kDa
Mass (kDA):
130.976 kDA
Human | |
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Location: | 1q25.3 |
Sequence: | 1; NC_000001.11 (183186264..183245127) |
The large variant is expressed only in specific epithelial cells of embryonic and neonatal tissues. In 17-week old embryo the small variant is found in cerebral cortex, lung, and distal tubes of kidney, but not in epithelia except for distal tubuli.
Secreted, extracellular space, extracellular matrix, basement membrane. Major component.
PMID: 1383240 by Kallunki P., et al. A truncated laminin chain homologous to the B2 chain: structure, spatial expression, and chromosomal assignment.
PMID: 8306988 by Vailly J., et al. The 100-kDa chain of nicein/kalinin is a laminin B2 chain variant.