EKC/KEOPS complex subunit LAGE3 (LAGE3)

Component of the EKC/KEOPS complex that's required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons starting with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.

LAGE3 functions as a dimerization module for the complex. .