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- Table of Contents
Facts about Keratin, type II cuticular Hb1.
Human | |
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Gene Name: | KRT81 |
Uniprot: | Q14533 |
Entrez: | 3887 |
Belongs to: |
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intermediate filament family |
ghHb1; ghHkb1; Hair keratin K2.9; hard keratin, type II, 1; Hb-1; hHAKB2-1; K81; keratin 81; Keratin, hair, basic, 1MLN 137; keratin, type II cuticular Hb1; keratin-81; KRTHB1HB1; Metastatic lymph node 137 gene protein; MLN137; Type II hair keratin Hb1; Type-II keratin Kb21
Mass (kDA):
54.928 kDA
Human | |
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Location: | 12q13.13 |
Sequence: | 12; NC_000012.12 (52285913..52291534, complement) |
Abundantly expressed in the differentiating cortex of growing (anagen) hair. Expression is restricted to the keratinocytes of the hair cortex and is absent from inner root sheath and medulla. Expressed in malignant lymph node tissue in breast carcinoma tissue.
PMID: 9457912 by Bowden P.E., et al. Characterization and chromosomal localization of human hair-specific keratin genes and comparative expression during the hair growth cycle.
PMID: 7556444 by Rogers M.A., et al. Sequence data and chromosomal localization of human type I and type II hair keratin genes.