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Krueppel-like factor 11 Antibodies
AND KLF11 ELISA kits, Krueppel-like factor 11 Proteins
Many biological assays use antibodies to detect Krueppel-like factor 11, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Krueppel-like factor 11 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Krueppel-like factor 11 antibodies...
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KLF11 Infographic by Boster Bio
All KLF11 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
ELISA
$480
Cat # EKC1625
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1625
1 kit, containing one 96-well plate and all necessary reagents
Human
IHC, WB
$523
Cat # M04277
100 µl
Cat # M04277
100 µl
KLF11 Overview
Facts about Krueppel-like factor 11.
Krueppel-like factor 11 (KLF11)
Transcription factor (PubMed:9748269, PubMed:10207080). Activates the epsilon- and gamma-globin gene promoters and, to a much lower level, the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth (PubMed:9748269, PubMed:10207080, PubMed:16131492).
Represses transcription of SMAD7 which enhances TGF-beta signaling (By similarity). Induces apoptosis (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | KLF11 |
| Uniprot: | O14901 |
| Entrez: | 8462 |
Family
| Belongs to: |
|---|
| Sp1 C2H2-type zinc-finger protein family |
Alternative Names
FKLFFKLF1; Krueppel-like factor 11; Kruppel-like factor 11; MODY7TGFB-inducible early growth response protein 2; TIEG-2; TIEG2TGFB inducible early growth response 2; Tieg3; Transforming growth factor-beta-inducible early growth response protein 2
Molecular Weight
Mass (kDA):
55.139 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2p25.1 |
| Sequence: | 2; NC_000002.12 (10043550..10054836) |
Tissue Specificity
Ubiquitous. Higher expression in erythroid cells.
Subcellular Localizations
Nucleus.
Diseases
- Neoplasms
- Diabetes Mellitus
- Diabetes Mellitus, Non-insulin-dependent
- Malignant Neoplasms
- Cell Transformation, Neoplastic
- Sudden Infant Death Syndrome
- Uterine Fibroids
- Dysequilibrium Syndrome
- Liver Carcinoma
- Depressive Disorder
- Uterine Neoplasms
- Neoplasm Metastasis
Interacting Proteins
- APPBP2
- TXNDC9
Pathways
- Cell Growth
- Cell Proliferation
- Methylation
- Localization
- Insulin Secretion
- Dna Methylation
- Cell Death
- Rna Interference
- Secretion
- Cell Activation
- Gene Silencing
- Chromatin Remodeling
- Regulation Of Cell Growth
PTMs
- Methylation
- Phosphorylation
Research Areas
- Cell Cycle and Replication
- Transcription Factors and Regulators
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KLF11
bosterbio.com/bosterbio-gene-info-cards/KLF11
References
PMID: 9748269 by Cook T., et al. Molecular cloning and characterization of TIEG2 reveals a new subfamily of transforming growth factor-beta-inducible Sp1-like zinc finger-encoding genes involved in the regulation of cell growth.
PMID: 10207080 by Asano H., et al. FKLF, a novel Kruppel-like factor that activates human embryonic and fetal beta-like globin genes.