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- Table of Contents
Facts about Bifunctional peptidase and arginyl-hydroxylase JMJD5.
Regulates expression of CCNA1 (cyclin-A1), leading to modulate cancer cell proliferation. In a complex with coregulator RCCD1, is also able to demethylate trimethylated 'Lys-36' (H3K36me3) of histone H3.
Mouse | |
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Gene Name: | Kdm8 |
Uniprot: | Q9CXT6 |
Entrez: | 77035 |
Belongs to: |
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No superfamily |
EC 1.14.11.27; FLJ13798; JmjC domain-containing protein 5; jumonji domain containing 5; Jumonji domain-containing protein 5; KDM8; lysine-specific demethylase 8
Mass (kDA):
47.145 kDA
Mouse | |
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Location: | 7|7 F3 |
Sequence: | 7; |
PMID: 30500822 by Saran A.R., et al. JMJD5 links CRY1 function and proteasomal degradation.