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- Table of Contents
6 Q&As
Facts about ER lumen protein-retaining receptor 3.
Also required for normal vesicular traffic through the Golgi. This receptor recognizes K-D-E-L (By similarity).
Human | |
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Gene Name: | KDELR3 |
Uniprot: | O43731 |
Entrez: | 11015 |
Belongs to: |
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ERD2 family |
ER lumen protein retaining receptor 3; ERD2L3; KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3; KDEL endoplasmic reticulum protein retention receptor 3; KDEL receptor 3
Mass (kDA):
25.027 kDA
Human | |
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Location: | 22q13.1 |
Sequence: | 22; NC_000022.11 (38468062..38483447) |
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPI-coated vesicle membrane; Multi-pass membrane protein. Localized in the Golgi in the absence of bound proteins with the sequence motif K-D-E-L. Trafficks back to the endoplasmic reticulum together with cargo proteins containing the sequence motif K-D-E-L.
PMID: 12529303 by Collins J.E., et al. Reevaluating human gene annotation: a second-generation analysis of chromosome 22.
PMID: 18086916 by Raykhel I., et al. A molecular specificity code for the three mammalian KDEL receptors.