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KRT16 Antibodies
AND KRT16 ELISA kits, KRT16 Proteins
Many biological assays use antibodies to detect KRT16, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KRT16 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KRT16 antibodies...
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KRT16 Infographic by Boster Bio
All KRT16 Products
Product
Figures
Specificity
Applications
Price
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M03393
100 μl
Cat # M03393
100 μl
Human, Mouse, Rat
ELISA
$480
Cat # EKC1322
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1322
1 kit, containing one 96-well plate and all necessary reagents
KRT16 Overview
Facts about Keratin, type I cytoskeletal 16.
Keratin, type I cytoskeletal 16 (KRT16)
Epidermis-specific type I keratin that plays an integral role in skin. Acts as a regulator of innate immunity in response to skin barrier violation: required for some inflammatory checkpoint for the skin barrier maintenance.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | KRT16 |
| Uniprot: | P08779 |
| Entrez: | 3868 |
Family
| Belongs to: |
|---|
| intermediate filament family |
Alternative Names
CK16; CK-16; cytokeratin 16; cytokeratin-16; FNEPPK; focal non-epidermolytic palmoplantar keratoderma; K16; K1CP; keratin 16; keratin, type I cytoskeletal 16; keratin-16; KRT16A; NEPPK
Molecular Weight
Mass (kDA):
51.268 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17q21.2 |
| Sequence: | 17; NC_000017.11 (41609778..41612767, complement) |
Tissue Specificity
Expressed in the hair follicle, nail bed and in mucosal stratified squamous epithelia and, suprabasally, in oral epithelium and palmoplantar epidermis. Also found in luminal cells of sweat and mammary gland ducts.
Diseases
- Pachyonychia Congenita
- Thickened Nails
- Palmoplantar Keratosis
- Dystrophy
- Dystrophia Unguium
- Neoplasms
- Hypertrophy
- Hyperkeratosis
- Carcinoma
- Psoriasis
- Malignant Neoplasms
- Leukokeratosis
Pathways
- Wound Healing
- Keratinocyte Proliferation
- Pathogenesis
- Catagen
- Cell Migration
- Keratinocyte Activation
- Cornification
- Osteoblast Differentiation
- Immune Response
- Endocytosis
- Lymphangiogenesis
- Localization
- Inflammatory Response
PTMs
- Phosphorylation
Research Areas
- Cell Biology
- Cellular Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KRT16
bosterbio.com/bosterbio-gene-info-cards/KRT16
References
PMID: 2431270 by Raychaudhury A., et al. Three tightly linked genes encoding human type I keratins: conservation of sequence in the 5'-untranslated leader and 5'-upstream regions of coexpressed keratin genes.
PMID: 2451124 by Rosenberg M., et al. A group of type I keratin genes on human chromosome 17: characterization and expression.