Kndc1 Antibodies

AND Kndc1 ELISA kits, Kndc1 Proteins

Many biological assays use antibodies to detect Kndc1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Kndc1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Kndc1 antibodies...

We validate the specificity of these antibodies to Kndc1 by testing them on tissues known to express Kndc1 positively and negatively. Browse below to find the Kndc1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Kndc1 Infographic by Boster Bio

All Kndc1 Products

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KNDC1 (NM_152643) Human Over-expression Lysate

Human

$960
Cat # LS085442
100 µg

Kndc1 Overview

Facts about Kinase non-catalytic C-lobe domain-containing protein 1.

Kinase non-catalytic C-lobe domain-containing protein 1 (Kndc1)

RAS-Guanine nucleotide exchange factor (GEF) that controls the negative regulation of neuronal dendrite growth by mediating a signaling pathway linking RAS and MAP2 (PubMed:17984326, PubMed:21385318). May be involved in cellular senescence (By similarity).

Gene Information

Mouse
Gene Name:	Kndc1
Uniprot:	Q0KK55
Entrez:	76484

Family

Belongs to:

No superfamily

Alternative Names

FLJ16067; kinase non-catalytic C-lobe domain (KIND) containing 1; member 2

Molecular Weight

Mass (kDA):
191.313 kDA

Genomic Context


Mouse

Location:	7\|7 F4
Sequence:	7;

Tissue Specificity

Highly expressed in the brain and at low levels in the ovary. In the brain it is most prominently expressed in the cerebellum where it is restricted to the granular Purkinje cell layer.

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Kndc1

References

PMID: 16099729 by Mees A., et al. Very-KIND is a novel nervous system specific guanine nucleotide exchange factor for Ras GTPases.

PMID: 16807365 by Nakayama M., et al. A gene-targeting approach for functional characterization of KIAA genes encoding extremely large proteins.