KLRC2 Antibodies

NKG2-C type II integral membrane protein (KLRC2)

Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. .

Gene Information

Human
Gene Name:	KLRC2
Uniprot:	P26717
Entrez:	3822

Family

Belongs to:
No superfamily

Alternative Names

CD159 antigen-like family member C; CD159c antigen; CD159c; killer cell lectin-like receptor subfamily C, member 2; KLRC2; MGC138244; NK cell receptor C; NKG2-C type II integral membrane protein; NKG2C; NKG2-C; NKG2CNKG2-C-activating NK receptor

Molecular Weight

Mass (kDA):
26.072 kDA

Genomic Context

Human
Location:	12p13.2
Sequence:	12; NC_000012.12 (10430599..10435993, complement)

Tissue Specificity

Natural killer cells.

Subcellular Localizations

Membrane; Single-pass type II membrane protein.

Diseases

• Cytomegalovirus Infections
• Hiv Infections
• Neoplasms
• Infective Disorder
• Virus Diseases
• Immunologic Deficiency Syndromes
• Leukemia
• Rheumatoid Arthritis
• Arthritis
• Lupus Erythematosus, Systemic
• Inflammation
• Innate Immune Response
• Autoimmunity

• Melanoma
• Rheumatism
• Malignant Neoplasms
• Lymphoma
• Hepatitis
• Hepatitis, Chronic
• Pre-eclampsia

Pathways

• Immune Response
• Pathogenesis
• Cell Activation
• Cytokine Production
• Secretion
• T Cell Activation
• Cytokine Secretion
• Translation
• Innate Immune Response
• Cell Development
• Cell Adhesion
• Adaptive Immune Response
• Hypersensitivity

• Inflammatory Response
• Reverse Transcription
• Mrna Splicing
• T Cell Proliferation
• Cell Differentiation
• Anagen
• Exocytosis

PTMs

• Phosphorylation

• Biotinylation

• Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KLRC2

Best Uses Of The KLRC2 Marker From Boster Bio

Boster Bio's Anti–NKG2C KLRC2 marker is one of many options you have when choosing flow procedures. Boster Bio offers optimization tips and guidance to answer any questions about the procedures. You'll find these guides and tips helpful in optimizing your experiments. This guide will give you the tools and information to create an experiment that is as accurate as possible.

Boster Bio Anti-NKG2C KLRC2Marker

Boster Bio offers anti-NKG2C KLRC2 markers that can be tested using both ELISA or WB assays. It reacts with Human and can be purchased in liquid form in PBS. You can learn more about the anti NKG2C marker by reading on. Alternatively, you can buy the kit and try it out for yourself!

Applications

KLRC2 can be found on chromosome 12,p13. It's conserved in humans, Rhesus monkeys and dogs. Currently, there are four orthologs of the human KLRC2 gene. This information is for reference only. These are just a few examples of how the KLRC2 marker can be used. These include:

(b). Genomic DNA extracted from peripheral blood, lymphodes, spleen, and spleens was purified using standard methods. Genotyping for the KLRC2 gene and FCGR3A gene was conducted using previously described protocols. Both genes were identified using a touchdownPCR on an agarose Gel containing Midori Green Advance. Amplicons were visualized using an iBright CL750 imaging system.

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