Plasma kallikrein Antibodies

AND KLKB1 ELISA kits, Plasma kallikrein Proteins

Many biological assays use antibodies to detect Plasma kallikrein, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Plasma kallikrein in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Plasma kallikrein antibodies...

We validate the specificity of these antibodies to Plasma kallikrein by testing them on tissues known to express KLKB1 positively and negatively. Browse below to find the KLKB1 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KLKB1 Infographic by Boster Bio

All KLKB1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Cleaved-Plasma Kallikrein HC (R390) KLKB1 Antibody

Human

$399
Cat # A04995
100μl

Anti-KLKB1 Monoclonal Antibody

7 Q&As

Human, Rat

IP, IHC, WB

$370
Cat # M04995
100 μl

Mouse Plasma Kallikrein/KLKB1 ELISA Kit PicoKine®

3 Q&As

Mouse

ELISA

$750
Cat # EK2107
96 wells/kit, with removable strips.

Anti-Cleaved-Plasma Kallikrein HC (R390) KLKB1 Antibody

Human

ELISA, IHC, WB

$380
Cat # A04995-1
100ul

Plasma Kallikrein 1B (KLKB1) (NM_000892) Human Recombinant Protein

$813
Cat # PROTP03952
20 µg

Plasma Kallikrein 1B (KLKB1) (NM_000892) Human Over-expression Lysate

Human

$960
Cat # LS003818
100 µg

KLKB1 Overview

Facts about Plasma kallikrein.

KLKB1 3D structure. Source: alphafold

Plasma kallikrein (KLKB1)

The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a mutual response, factor XII following its binding to a negatively charged surface.

Additionally, it releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin. .

Gene Information

Human
Gene Name:	KLKB1
Uniprot:	P03952
Entrez:	3818

Family

Belongs to:

peptidase S1 family

Alternative Names

EC 3.4.21; EC 3.4.21.34; Fletcher factor; kallikrein B, plasma (Fletcher factor) 1; kininogenin; KLK3plasma kallikrein; KLKB1; plasma kallikrein heavy chain; plasma kallikrein light chain; Plasma Kallikrein; Plasma Prekallikrein; PPK

Molecular Weight

Mass (kDA):
71.37 kDA

Genomic Context


Human

Location:	4q35.2
Sequence:	4; NC_000004.12 (186215714..186258477)

Subcellular Localizations

Secreted.

Diseases

Malignant Neoplasms
Malignant Neoplasm Of Lung
Venous Thrombosis
Deep Vein Thrombosis
Thrombosis
Carcinoma
Lung Neoplasms
Thrombophilia
Hypertensive Disease
Essential Hypertension
Stenosis
Infarction
Malignant Neoplasm Of Breast

Pulmonary Embolism
Thromboembolism
Muscular Dystrophy, Facioscapulohumeral
Unbalanced Translocation
Carcinogenesis
Myocardial Infarction
Venous Thromboembolism

Pathways

Coagulation
Blood Coagulation
Methylation
Mammary Gland Involution
Cell Proliferation
Aging
Dna Methylation
Glycosylation

Pathogenesis
Localization
Epithelial Cell Proliferation

PTMs

Demethylation

Biotinylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KLKB1

References

PMID: 3521732 by Chung D.W., et al. Human plasma prekallikrein, a zymogen to a serine protease that contains four tandem repeats.

PMID: 11031105 by Yu H., et al. Genomic structure of the human plasma prekallikrein gene, identification of allelic variants, and analysis in end-stage renal disease.