Krueppel-like factor 8 Antibodies

AND KLF8 ELISA kits, Krueppel-like factor 8 Proteins

Many biological assays use antibodies to detect Krueppel-like factor 8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Krueppel-like factor 8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Krueppel-like factor 8 antibodies...

We validate the specificity of these antibodies to Krueppel-like factor 8 by testing them on tissues known to express KLF8 positively and negatively. Browse below to find the KLF8 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KLF8 Infographic by Boster Bio

All KLF8 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Krueppel-like factor 8 KLF8 Antibody Picoband®

6 Q&As

Human

$370
Cat # PA1890
100 μg/vial

Anti-Krueppel-like factor 8 KLF8 Antibody

Human

ELISA, IHC

$380
Cat # A04646
100ul

KLF8 (NM_007250) Human Over-expression Lysate

Human

$628
Cat # LS011279
100 µg

KLF8 Overview

Facts about Krueppel-like factor 8.

KLF8 3D structure. Source: alphafold

Krueppel-like factor 8 (KLF8)

Transcriptional repressor and activator. Binds to CACCC- boxes promoter elements.

Also binds the GT-box of cyclin D1 promoter and mediates cell cycle progression at G(1) phase as a downstream target of focal adhesion kinase (FAK). .

Gene Information

Human
Gene Name:	KLF8
Uniprot:	O95600
Entrez:	11279

Family

Belongs to:

Sp1 C2H2-type zinc-finger protein family

Alternative Names

Basic krueppel-like factor 3; basic kruppel-like factor 3; BKLF3DKFZp686O08126; DXS741; Krueppel-like factor 8; Kruppel-like factor 8; Zinc finger protein 741; ZNF741MGC138314

Molecular Weight

Mass (kDA):
39.314 kDA

Genomic Context


Human

Location:	Xp11.21
Sequence:	X; NC_000023.11 (55908123..56291531)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Nucleus.

Diseases

Malignant Neoplasms
Neoplasms
Cell Invasion
Malignant Neoplasm Of Breast
Tissue Adhesions
Neoplasm Metastasis
Carcinoma
Tumor Progression
Neoplasm Invasiveness
Liver Carcinoma
Carcinogenesis
Renal Cell Carcinoma
Mammary Neoplasms

Cell Transformation, Neoplastic
Glioblastoma
Malignant Neoplasm Of Stomach
Liver Neoplasms
Stomach Neoplasms
Non-neoplastic Disorder
Metastatic Malignant Neoplasm To The Lung

Pathways

Cell Cycle
Cell Proliferation
Epithelial To Mesenchymal Transition
Cell Growth
Cell Migration
Localization
Rna Interference
Cell Adhesion
Cell Death
Transport
Gene Silencing
Stem Cell Maintenance
Cell Fate Determination

Nuclear Export
Cell Cycle Arrest
Nuclear Transport
Reverse Transcription
Histone Acetylation
Oncogenesis
Regulation Of Cell Cycle

PTMs

Sumoylation
Phosphorylation

Acetylation
Cleavage

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KLF8

References

PMID: 23134681 by Camacho-Vanegas O., et al. Shaking the family tree: Identification of novel and biologically active alternatively spliced isoforms across the KLF family of transcription factors.

PMID: 10756197 by van Vliet J., et al. Human Kruppel-like factor 8: a CACCC-box binding protein that associates with CtBP and represses transcription.