KIR2DS2 Antibodies

AND KIR2DS2 ELISA kits, KIR2DS2 Proteins

Many biological assays use antibodies to detect KIR2DS2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KIR2DS2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KIR2DS2 antibodies...

We validate the specificity of these antibodies to KIR2DS2 by testing them on tissues known to express KIR2DS2 positively and negatively. Browse below to find the KIR2DS2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KIR2DS2 Infographic by Boster Bio

All KIR2DS2 Products

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Product

Figures

Specificity

Applications

Price

Anti-KIR2DS2 Antibody

Human

ELISA, IF, ICC, WB

$449
Cat # A03789
0.1 mg

KIR2DS2 (NM_012312) Human Over-expression Lysate

Human

$628
Cat # LS100132285
100 µg

KIR2DS2 Overview

Facts about Killer cell immunoglobulin-like receptor 2DS2.

KIR2DS2 3D structure. Source: alphafold

Killer cell immunoglobulin-like receptor 2DS2 (KIR2DS2)

Receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells.

Gene Information

Human
Gene Name:	KIR2DS2
Uniprot:	P43631
Entrez:	100132285

Family

Belongs to:

immunoglobulin superfamily

Alternative Names

183ActI; CD158b; CD158j; Cl-49; killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2; KIR2DS2; NKAT5; p58 KIR; p58 NK Receptor CL-49

Molecular Weight

Mass (kDA):
33.502 kDA

Genomic Context


Human

Location:	19q13.4
Sequence:	19; NT_113949.2 (122955..137265, complement)

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein.

Diseases

Arthritis
Rheumatoid Arthritis
Leukemia
Graft-vs-host Disease
Autoimmune Reaction
Malignant Neoplasms
Hepatitis
Autoimmune Diseases
Vasculitis
Autoimmunity
Dysequilibrium Syndrome
Myeloid Leukemia
Acute Gvh Disease

Inflammation
Virus Diseases
Hepatitis, Chronic
Sclerosis
Cytomegalovirus Infections
Hepatitis C
Arthritis, Psoriatic

Pathways

Pathogenesis
Cell Activation
Cell Proliferation
Cytolysis
Secretion
Senescence
Cell Division
Transport
T Cell Activation
Interferon-gamma Production
Immune Response
Methylation

Replicative Senescence
T Cell Proliferation
Cell Differentiation
Cell Growth
Cell Recognition
Lymphocyte Activation

PTMs

Phosphorylation

Citrullination

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KIR2DS2

References

PMID: 7749980 by Wagtmann N., et al. Molecular clones of the p58 NK cell receptor reveal immunoglobulin- related molecules with diversity in both the extra- and intracellular domains.

PMID: 7716543 by Colonna M., et al. Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells.