KIF2C Antibodies

AND KIF2C ELISA kits, KIF2C Proteins

Many biological assays use antibodies to detect KIF2C, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KIF2C in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KIF2C antibodies...

We validate the specificity of these antibodies to KIF2C by testing them on tissues known to express KIF2C positively and negatively. Browse below to find the KIF2C antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KIF2C Infographic by Boster Bio

All KIF2C Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-MCAK/KIF2C Antibody Picoband®

8 Q&As

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # PB9230
100 μg/vial

Anti-Phospho-KIF2C (S95) Antibody

Human, Mouse

ELISA, IF, WB

$380
Cat # A03202S95
100ul

Anti-MCAK (KIF2C) Mouse Monoclonal Antibody [Clone ID: OTI1C5]

Human, Monkey, Mouse, Rat

Flow Cytometry, IF, IHC, WB

$523
Cat # M03202
100 µl

Anti-MCAK Rabbit Monoclonal Antibody

Human

Flow Cytometry, IF, ICC, WB

$370
Cat # M03202-1
100 μl/vial

MCAK (KIF2C) (NM_006845) Human Over-expression Lysate

Human

$628
Cat # LS011004
100 µg

KIF2C Overview

Facts about Kinesin-like protein KIF2C.

KIF2C 3D structure. Source: alphafold

Kinesin-like protein KIF2C (KIF2C)

In complex with KIF18B, constitutes the significant microtubule plus-end depolymerizing activity in mitotic cells (PubMed:21820309). Regulates the turnover of microtubules in the kinetochore and functions in chromosome segregation during mitosis (PubMed:19060894).

Plays a role in chromosome congression and is required for the lateral to end-on conversion of the chromosome- microtubule attachment (PubMed:23891108). .

Gene Information

Human
Gene Name:	KIF2C
Uniprot:	Q99661
Entrez:	11004

Family

Belongs to:

TRAFAC class myosin-kinesin ATPase superfamily

Alternative Names

kinesin family member 2C; kinesin-like 6 (mitotic centromere-associated kinesin); Kinesin-like protein 6; kinesin-like protein KIF2C; MCAKKNSL6kinesin-like 6; Mitotic centromere-associated kinesin

Molecular Weight

Mass (kDA):
81.313 kDA

Genomic Context


Human

Location:	1p34.1
Sequence:	1; NC_000001.11 (44739704..44767767)

Tissue Specificity

Expressed at high levels in thymus and testis, at low levels in small intestine, the mucosal lining of colon, and placenta, and at very low levels in spleen and ovary; expression is not detected in prostate, peripheral blood Leukocytes, heart, brain, lung, liver, skeletal muscle, kidney or pancreas. Isoform 2 is testis-specific.

Subcellular Localizations

Cytoplasm, cytoskeleton. Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Associates with the microtubule network at the growing distal tip (the plus-end) of microtubules, probably through interaction with MTUS2/TIP150 and MAPRE1 (By similarity). Association with microtubule plus ends is also mediated by interaction with KIF18B. Centromeric localization requires the presence of BUB1 and SGO2.