KDSR Antibodies

AND KDSR ELISA kits, KDSR Proteins

Many biological assays use antibodies to detect KDSR, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KDSR in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KDSR antibodies...

We validate the specificity of these antibodies to KDSR by testing them on tissues known to express KDSR positively and negatively. Browse below to find the KDSR antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KDSR Infographic by Boster Bio

All KDSR Products

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Applications

Price

FVT1 (KDSR) (NM_002035) Human Recombinant Protein

$1062
Cat # PROTQ06136
20 µg

FVT1 (KDSR) (NM_002035) Human Over-expression Lysate

Human

$628
Cat # LS002531
100 µg

KDSR Overview

Facts about 3-ketodihydrosphingosine reductase.

KDSR 3D structure. Source: alphafold

3-ketodihydrosphingosine reductase (KDSR)

Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) into dihydrosphingosine (DHS). .

Gene Information

Human
Gene Name:	KDSR
Uniprot:	Q06136
Entrez:	2531

Family

Belongs to:

short-chain dehydrogenases/reductases (SDR) family

Alternative Names

3-ketodihydrosphingosine reductase; DHSR; EC 1.1.1.102,3-dehydrosphinganine reductase; FLJ36555; FLJ92680; follicular lymphoma variant translocation 1; Follicular variant translocation protein 1; FVT-1; FVT1KDS reductase; SDR35C1; short chain dehydrogenase/reductase family 35C, member 1

Molecular Weight

Mass (kDA):
36.187 kDA

Genomic Context


Human

Location:	18q21.33
Sequence:	18; NC_000018.10 (63327726..63367234, complement)

Tissue Specificity

Expressed in all tissues examined. Highest expression in placenta. High expression in lung, kidney, stomach and small intestine, low expression in heart, spleen and skeletal muscle. Weakly expressed in normal hematopoietic tissues. Higher expression in some T-cell malignancies and PHA-stimulated lymphocytes.

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Diseases

Erythrokeratodermia variabilis et progressiva 4 (EKVP4)

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KDSR

References

PMID: 8417785 by Rimokh R., et al. FVT-1, a novel human transcription unit affected by variant translocation t(2;18)(p11;q21) of follicular lymphoma.

PMID: 15328338 by Kihara A., et al. FVT-1 is a mammalian 3-ketodihydrosphingosine reductase with an active site that faces the cytosolic side of the endoplasmic reticulum membrane.