KCNT1 Antibodies

AND KCNT1 ELISA kits, KCNT1 Proteins

Many biological assays use antibodies to detect KCNT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KCNT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KCNT1 antibodies...

We validate the specificity of these antibodies to KCNT1 by testing them on tissues known to express KCNT1 positively and negatively. Browse below to find the KCNT1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KCNT1 Infographic by Boster Bio

All KCNT1 Products

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Product

Figures

Specificity

Applications

Price

Anti-KCNT1 Antibody

7 Q&As

Human, Mouse, Rat

ELISA, IHC-P, WB, IF (paraffin)

$335
Cat # A05367-1
100ul

Anti-KCNT1 Antibody

Human, Mouse, Rat

ELISA, IHC, WB

$380
Cat # A05367
100ul

KCNT1 (NM_020822) Human Over-expression Lysate

Human

$960
Cat # LS057582
100 µg

KCNT1 Overview

Facts about Potassium channel subfamily T member 1.

KCNT1 3D structure. Source: alphafold

Potassium channel subfamily T member 1 (KCNT1)

Outwardly rectifying potassium channel subunit that may coassemble with other Slo-type channel subunits. Activated by high intracellular sodium or chloride levels.

Activated upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1. May be regulated by calcium in the absence of sodium ions (in vitro) (By similarity).

Gene Information

Human
Gene Name:	KCNT1
Uniprot:	Q5JUK3
Entrez:	57582

Family

Belongs to:

potassium channel family

Alternative Names

Potassium channel subfamily T member 1

Molecular Weight

Mass (kDA):
138.343 kDA

Genomic Context


Human

Location:	9q34.3
Sequence:	9; NC_000009.12 (135702185..135795502)

Tissue Specificity

Highest expression in liver, brain and spinal cord. Lowest expression in skeletal muscle.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Epileptic encephalopathy, early infantile, 14 (EIEE14)

PTMs

Glycoprotein

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KCNT1

References

PMID: 20512134 by Brown M.R., et al. Fragile X mental retardation protein controls gating of the sodium- activated potassium channel Slack.

PMID: 23086396 by Heron S.E., et al. Missense mutations in the sodium-gated potassium channel gene KCNT1 cause severe autosomal dominant nocturnal frontal lobe epilepsy.