KCNMB3 Antibodies

AND KCNMB3 ELISA kits, KCNMB3 Proteins

Many biological assays use antibodies to detect KCNMB3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KCNMB3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KCNMB3 antibodies...

We validate the specificity of these antibodies to KCNMB3 by testing them on tissues known to express KCNMB3 positively and negatively. Browse below to find the KCNMB3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: SEPTIN9 Next: TRAPPC3

KCNMB3 Infographic by Boster Bio

All KCNMB3 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-KCMB3 KCNMB3 Antibody

Human

ELISA, WB

$380
Cat # A09781
100ul

Human KCNMB3 Recombinant Protein

SDS-PAGE, Denatured

$250
Cat # PROTQ9NPA1
Starting from 20ug

KCNMB3 (NM_171828) Human Over-expression Lysate

Human

$628
Cat # LS027094
100 µg

KCNMB3 Overview

Facts about Calcium-activated potassium channel subunit beta-3.

KCNMB3 3D structure. Source: alphafold

Calcium-activated potassium channel subunit beta-3 (KCNMB3)

Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby leading to KCNMA1 channel diversity.

Alters the functional properties of the current expressed by the KCNMA1 channel. Isoform 2, isoform 3 and isoform 4 partially inactivate the current of KCNBMA.

Gene Information

Human
Gene Name:	KCNMB3
Uniprot:	Q9NPA1
Entrez:	27094

Family

Belongs to:

KCNMB (TC 8.A.14.1) family

Alternative Names

BK channel subunit beta-3; BKbeta3; Hbeta3; KCNMB2; KCNMBL; potassium large conductance calcium-activated channel, subfamily M beta member3; slo-beta-3; subfamily M subunit beta-3; voltage and Ca2+ activated potassium channel Maxi K beta 3subunit

Molecular Weight

Mass (kDA):
31.604 kDA

Genomic Context


Human

Location:	3q26.32
Sequence:	3; NC_000003.12 (179239749..179267050, complement)

Tissue Specificity

Isoform 1, isoform 3 and isoform 4 are widely expressed. Isoform 2 is expressed placenta, pancreas, kidney and heart. Isoform 1 and isoform 3 are highly expressed in pancreas and testis.

Subcellular Localizations

Membrane; Multi-pass membrane protein.

Diseases

Epilepsy
Epilepsy, Generalized
Adenocarcinoma
Malignant Squamous Cell Neoplasm
Lung Neoplasms
Congenital Abnormality
Non-small Cell Lung Carcinoma
Idiopathic Generalized Epilepsy
Absence Epilepsy
Chorea
Malignant Neoplasm Of Lung
Carcinoma

Carcinogenesis
Dyskinetic Syndrome
Malignant Neoplasms
Epilepsies, Myoclonic
Dyskinesia, Paroxysmal
Cytogenetic Abnormality
Febrile Convulsions

Pathways

Synaptic Transmission
Osteoblast Proliferation
Pathogenesis

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KCNMB3

References

PMID: 10585773 by Riazi M.A., et al. Identification of a putative regulatory subunit of a calcium- activated potassium channel in the dup(3q) syndrome region and a related sequence on 22q11.2.

PMID: 10692449 by Brenner R., et al. Cloning and functional characterization of novel large conductance calcium-activated potassium channel beta subunits, hKCNMB3 and hKCNMB4.