KCNK6 Antibodies

AND KCNK6 ELISA kits, KCNK6 Proteins

Many biological assays use antibodies to detect KCNK6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KCNK6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KCNK6 antibodies...

We validate the specificity of these antibodies to KCNK6 by testing them on tissues known to express KCNK6 positively and negatively. Browse below to find the KCNK6 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KCNK6 Infographic by Boster Bio

All KCNK6 Products

Product

Figures

Specificity

Applications

Price

Anti-TWIK-2 KCNK6 Antibody

Human

ELISA, WB

$380
Cat # A10559
100ul

KCNK6 (NM_004823) Human Recombinant Protein

$1249
Cat # PROTQ9Y257
20 µg

KCNK6 (NM_004823) Human Over-expression Lysate

Human

$628
Cat # LS009424
100 µg

KCNK6 Overview

Facts about Potassium channel subfamily K member 6.

KCNK6 3D structure. Source: alphafold

Potassium channel subfamily K member 6 (KCNK6)

Exhibits outward rectification in a physiological K(+) gradient and mild inward rectification in symmetrical K(+) conditions. .

Gene Information

Human
Gene Name:	KCNK6
Uniprot:	Q9Y257
Entrez:	9424

Family

Belongs to:

two pore domain potassium channel (TC 1.A.1.8) family

Alternative Names

Inward rectifying potassium channel protein TWIK-2; K2P6.1 potassium channel; K2p6.1; potassium channel subfamily K member 6; potassium channel, subfamily K, member 6; TOSSFLJ12282; TWIK-2; TWIK2KCNK8; TWIK-originated similarity sequence; TWIK-originated sodium similarity sequence

Molecular Weight

Mass (kDA):
33.747 kDA

Genomic Context


Human

Location:	19q13.2
Sequence:	19; NC_000019.10 (38319845..38332076)

Tissue Specificity

Widespread expression, detected in all tissues tested except for skeletal muscle. Strongest expression in placenta, pancreas, heart, colon and spleen, lower levels detected in peripheral blood leukocytes, lung, liver, kidney and thymus. Lowest expression detected in brain.

Subcellular Localizations

Membrane; Multi-pass membrane protein.

Diseases

Cystic Fibrosis
Fibrosis
Circling Gait
Complete Hearing Loss
Cardiac Arrhythmia
Anemia
Long Qt Syndrome
Anemia, Sickle Cell
Pseudohypoaldosteronism
Hypertensive Disease
Nervousness

Pain
Steroid Sulfatase Deficiency Disease
Inflammation
Chimera Disorder
Stress, Psychological
Pathologic Vasoconstriction

Pathways

Secretion
Reverse Transcription
Localization
Transport
Response To Stress
Muscle Cell Migration
Cell Migration
Smooth Muscle Cell Migration

Cellular Localization
Ion Transport

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KCNK6

References

PMID: 10359073 by Pountney D.J., et al. Identification and cloning of TWIK-originated similarity sequence (TOSS): a novel human 2-pore K+ channel principal subunit.

PMID: 10075682 by Chavez R.A., et al. TWIK-2, a new weak inward rectifying member of the tandem pore domain potassium channel family.