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- Table of Contents
Facts about G protein-activated inward rectifier potassium channel 1.
Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
Human | |
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Gene Name: | KCNJ3 |
Uniprot: | P48549 |
Entrez: | 3760 |
Belongs to: |
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inward rectifier-type potassium channel (TC 1.A.2.1) family |
G protein-activated inward rectifier potassium channel 1; GIRK-1; GIRK1Kir3.1; Inward rectifier K(+) channel Kir3.1; inward rectifier K+ channel KIR3.1; KGA; KIR3.1; Potassium channel, inwardly rectifying subfamily J member 3; potassium inwardly-rectifying channel, subfamily J, member 3
Mass (kDA):
56.603 kDA
Human | |
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Location: | 2q24.1 |
Sequence: | 2; NC_000002.12 (154698581..154858354) |
Membrane; Multi-pass membrane protein.
PMID: 8868049 by Chan K.W., et al. A recombinant inwardly rectifying potassium channel coupled to GTP- binding proteins.
PMID: 8804710 by Schoots O., et al. Cloning of a G protein-activated inwardly rectifying potassium channel from human cerebellum.