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- Table of Contents
Facts about Potassium voltage-gated channel subfamily B member 2.
Can form functional homotetrameric and heterotetrameric channels which contain variable proportions of KCNB1; station properties are based on the type of alpha subunits which are part of the station. Can also form functional heterotetrameric channels with other alpha subunits which are non- running when expressed independently, such as KCNS1 and KCNS2, creating a functionally diverse assortment of channel complexes.
Human | |
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Gene Name: | KCNB2 |
Uniprot: | Q92953 |
Entrez: | 9312 |
Belongs to: |
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potassium channel family |
delayed rectifier potassium channel protein; KCNB2; KV2.2; Potassium Channel Kv2.2; potassium voltage-gated channel subfamily B member 2; potassium voltage-gated channel, Shab-related subfamily, member 2; voltage-gated potassium channel subunit Kv2.2
Mass (kDA):
102.563 kDA
Human | |
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Location: | 8q21.11 |
Sequence: | 8; NC_000008.11 (72537225..72945890) |
Cell membrane; Multi-pass membrane protein. Perikaryon. Cell projection, dendrite. Localized uniformly throughout cell bodies and dendrites. Colocalizes with KCNB1 to high-density somatodendritic clusters on cortical pyramidal neurons.
PMID: 9612272 by Schmalz F., et al. Molecular identification of a component of delayed rectifier current in gastrointestinal smooth muscles.
PMID: 10414301 by Coetzee W.A., et al. Molecular diversity of K+ channels.