KCNA6 Antibodies

Potassium voltage-gated channel subfamily A member 6 (KCNA6)

Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Types tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient (PubMed:2347305, PubMed:14575698).

The channel alternates between opened and closed conformations in response to the voltage difference across the membrane (PubMed:2347305, PubMed:14575698). Can form operational homotetrameric channels and heterotetrameric channels which contain varying proportions of KCNA1, KCNA2, KCNA4, KCNA6, and possibly other family members too; channel properties depend on the type of alpha subunits which are part of the channel (By similarity).

Gene Information

Human
Gene Name:	KCNA6
Uniprot:	P17658
Entrez:	3742

Family

Belongs to:
potassium channel family

Alternative Names

FLJ25134; HBK2; human brain potassium channel-2; KV1.6; potassium voltage-gated channel subfamily A member 6; potassium voltage-gated channel, shaker-related subfamily, member 6; Voltage-gated potassium channel HBK2; voltage-gated potassium channel protein Kv1.6; Voltage-gated potassium channel subunit Kv1.6

Molecular Weight

Mass (kDA):
58.729 kDA

Genomic Context

Human
Location:	12p13.32
Sequence:	12; NC_000012.12 (4806877..4851927)

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

• Isaacs Syndrome
• Myokymia
• Thymus Neoplasms
• Ataxia
• Thymoma
• Diabetes Mellitus
• Autoimmune Diseases
• Peripheral Neuropathy
• Vascular Diseases
• Alzheimer's Disease
• Autoimmunity
• Myasthenias

• Adenoma
• Muscular Fasciculation
• Dementia
• Carcinoma
• Opisthotonus
• Episodic Ataxia Type 1

Interacting Proteins

• DOLK

Pathways

• Pathogenesis
• Signal Transmission
• Localization

PTMs

• Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KCNA6

Boster Bio Anti-KCNA6 Marker Review

This article will explain everything you need to know before you buy Boster Bio Anti KCNA6 Marker. Learn about the company's past, high-affinity prima antibodies, and the many uses for KCNA6 MAb. This information is available to all scientists around world. Let's take a closer look at the Boster Bio Anti-KCNA6 Marker.

Boster Bio Anti KCNA6 Signer

Boster Bio Anti-KCNA6 marker may be useful if you need KCNA6 to be detected in your samples. These monoclonal antibodies are non-hazardous. Blocking peptides can be purchased depending on the length and complexity of your immunogen. Boster Bio validates all of their antibodies using both positive and negative samples. This ensures that they work as planned.

Boster Bio's history

If you are interested in biotechnology as a career, you might be curious about the company's past and promoters. This review will provide information about Boster Bio's history and career opportunities. We will also share the most recent recruitment news from Boster Bio. We hope you enjoy reading! In the meantime, you can learn more about their current recruitment opportunities and how to apply for them. We have also compiled the names of key people in the company to help you decide whether you want to apply.

In a nutshell, Boster Bio is an antibody manufacturer that has been focusing on pathology for years. They specialize in ELISA assay analysis and high-throughput screening of data. Multiplex IHC services are a great way to identify multiple targets at once with quick turnaround. You'll also benefit from their expertise in immunogen design. Boster Bio's IHC services have been the focus of many scientific articles and have contributed to more than 5,000 scientific publications.

Boster's high-affinity prima antibodies

Several studies have shown that Boster's high-affinity primary antibody uses the KCNA6 marker to recognize a broad spectrum of proteins. This is supported by the availability a wide range antibodies. In addition to the KCNA6 marker, this antibody also recognizes many other targets, such as phosphorylated glycine, lysine, and cysteine. Multiplexing and visualization of binding have been used to demonstrate the antibody's high affinity.

Validating the performance and reproducibility of antibodies is key to reproducibility. To do this, the user must conduct a well designed experiment and validate the antibody performance. A vendor should provide quality antibodies and detailed disclosure of its methods. Publishers can help overcome the reproducibility crisis by implementing guidelines for validation and data reporting. Antibody researchers can improve their research' quality and reliability by working together.

Without a specific marker it can be difficult or impossible to detect high-affinity primary antibody. Using this marker, Boster has designed an antibody that targets the KCNA6 protein on tumor cells. This antibody has a therapeutic impact in hepatocellular and other inflammatory disease, but it is difficult for clinicians to control its pharmacokinetics. However, it is a promising therapy.