KCNA3 Antibodies

AND KCNA3 ELISA kits, KCNA3 Proteins

Many biological assays use antibodies to detect KCNA3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KCNA3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KCNA3 antibodies...

We validate the specificity of these antibodies to KCNA3 by testing them on tissues known to express KCNA3 positively and negatively. Browse below to find the KCNA3 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KCNA3 Infographic by Boster Bio

All KCNA3 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-KCNA3 Antibody Picoband®

1 Q&As

Human, Mouse, Rat

$370
Cat # PB9650
100 μg/vial

Anti-Kv1.3 (E131) KCNA3 Antibody

Human, Mouse, Rat

IF, IHC

$405
Cat # A03981
100ul

Anti-Phospho-Kv1.3 (Y187) KCNA3 Antibody

Human, Mouse, Rat

ELISA, IF, IHC, WB

$380
Cat # A03981Y187
100ul

KCNA3 (NM_002232) Human Over-expression Lysate

Human

$628
Cat # LS003738
100 µg

KCNA3 Overview

Facts about Potassium voltage-gated channel subfamily A member 3.

KCNA3 3D structure. Source: alphafold

Potassium voltage-gated channel subfamily A member 3 (KCNA3)

Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.

Gene Information

Human
Gene Name:	KCNA3
Uniprot:	P22001
Entrez:	3738

Family

Belongs to:

potassium channel family

Alternative Names

HGK5; HLK3KV1.3; HPCN3PCN3; HUKIII; Kv1.3; MK3; potassium channel 3; potassium voltage-gated channel subfamily A member 3; potassium voltage-gated channel, shaker-related subfamily, member 3; type n potassium channel; Voltage-gated K(+) channel HuKIII; voltage-gated potassium channel protein Kv1.3; Voltage-gated potassium channel subunit Kv1.3

Molecular Weight

Mass (kDA):
63.842 kDA

Genomic Context


Human

Location:	1p13.3
Sequence:	1; NC_000001.11 (110653560..110674940, complement)

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Autoimmune Reaction
Autoimmune Diseases
Multiple Sclerosis
Sclerosis
Nervousness
Decreased Immunologic Activity [pe]
Experimental Autoimmune Encephalomyelitis
Malignant Neoplasms
Inflammation
Encephalomyelitis
Neoplasms
Delayed Hypersensitivity
Disease Of Adrenal Medulla

Hypoxia
Pathologic Vasoconstriction
Neuroblastoma
Alzheimer's Disease
Hyperplasia
Diabetes Mellitus
Edema

Interacting Proteins

BAX
DOLK

Pathways

Localization
Cell Activation
T Cell Activation
Cell Proliferation
Pathogenesis
Transport
T Cell Proliferation
Secretion
Hypersensitivity
Lymphocyte Proliferation
Immune Response
Glucose Homeostasis
Cell Differentiation

Lymphocyte Activation
Inflammatory Response
Induction Of Apoptosis
Respiratory Burst
Cell Death
Bone Resorption
Cell Adhesion

PTMs

Phosphorylation
Carboxylation
Cleavage

Glycosylation
Amidation
Dephosphorylation

Iodination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KCNA3

References

PMID: 7829094 by Folander K., et al. Confirmation of the assignment of the gene encoding Kv1.3, a voltage- gated potassium channel (KCNA3) to the proximal short arm of human chromosome 1.

PMID: 1986382 by Philipson L.H., et al. Sequence and functional expression in Xenopus oocytes of a human insulinoma and islet potassium channel.