This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Histone acetyltransferase KAT7.
During chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Acts as a coactivator of the licensing variable CDT1 (PubMed:18832067).
Human | |
---|---|
Gene Name: | KAT7 |
Uniprot: | O95251 |
Entrez: | 11143 |
Belongs to: |
---|
MYST (SAS/MOZ) family |
HBO1EC 2.3.1.48; HBOA; Histone acetyltransferase binding to ORC1; histone acetyltransferase MYST2; KAT7; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2; MYST histone acetyltransferase 2; MYST-2
Mass (kDA):
70.642 kDA
Human | |
---|---|
Location: | 17q21.33 |
Sequence: | 17; NC_000017.11 (49788681..49835026) |
Ubiquitously expressed, with highest levels in testis.
Nucleus, nucleoplasm. Cytoplasm, cytosol. Nucleus. Associates with replication origins specifically during the G1 phase of the cell cycle (PubMed:18832067).
PMID: 10438470 by Iizuka M., et al. Histone acetyltransferase HBO1 interacts with the ORC1 subunit of the human initiator protein.
PMID: 10930412 by Sharma M., et al. Androgen receptor interacts with a novel MYST protein, HBO1.