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- Table of Contents
Facts about Histone acetyltransferase KAT6B.
May be involved in cerebral cortex development. Component of the MOZ/MORF complex that has a histone H3 acetyltransferase activity.
Human | |
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Gene Name: | KAT6B |
Uniprot: | Q8WYB5 |
Entrez: | 23522 |
Belongs to: |
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MYST (SAS/MOZ) family |
DKFZp313G1618; FLJ90335; Histone acetyltransferase MORF; Histone acetyltransferase MOZ2; histone acetyltransferase MYST4; KAT6B; KIAA0383; Monocytic leukemia zinc finger protein-related factor; MORFMorf; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4; MOZ2EC 2.3.1.48; MOZ-related factor; MYST histone acetyltransferase (monocytic leukemia) 4; MYST-4; qkf; querkopf
Mass (kDA):
231.378 kDA
Human | |
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Location: | 10q22.2 |
Sequence: | 10; NC_000010.11 (74824927..75032624) |
Ubiquitously expressed, with high levels in heart, pancreas, testis and ovary.
Nucleus.
PMID: 10497217 by Champagne N., et al. Identification of a human histone acetyltransferase related to monocytic leukemia zinc finger protein.
PMID: 11157802 by Panagopoulos I., et al. Fusion of the MORF and CBP genes in acute myeloid leukemia with the t(10;16)(q22;p13).