This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Jerky protein homolog.
May bind DNA.
..
Human | |
---|---|
Gene Name: | JRK |
Uniprot: | O75564 |
Entrez: | 8629 |
Belongs to: |
---|
tigger transposable element derived protein family |
DKFZp686C24207; FLJ45729; jerky homolog (mouse); jerky protein homolog; JH8jerky (mouse) homolog
Mass (kDA):
61.815 kDA
Human | |
---|---|
Location: | 8q24.3 |
Sequence: | 8; NC_000008.11 (142651501..142669983, complement) |
Expressed ubiquitously.
Nucleus.
You've probably heard of the Boster Bio Anti-JRK Antibody Picoband. You may not be familiar with this antibody. What is it, and why is it important? Read on to find out! It is an antibody that detects GAPDH (Forward 5-GGACCACCAACTGCTT; reverse 5'-GTCTTGGACACAG).
The Boster Bio Anti-JRK Immunoglobulin is a commercially available product with a catalog number of A15261. The antibody reacts with Human and has a shelf life of up to one year at -20degC. Its other ingredients include 0.2mg Na2HPO4 and 4mg Trehalose. Researchers who are interested in receiving product credit can submit their data for species validation and application validation. These credits can be used by all scientists around the globe.
We used a b–actin MUT-3’ UTR construct and miR-644a to mutate the miR-644a target location by inserting two nucleotides in the seed matching area. These nucleotides were mutated to disrupt the base-pairing relationship between the miR-644a target MRNA and the target MiRNA.
The positional data in the downloadable entries is based around the canonical sequence of GAPDH. This information is intended for research purposes and is not a substitute for professional medical advice. The staff of NCBI are biochemists, biologists, and they do not make any medical recommendations or diagnose disease.
OCBs are found in serum, cerebrospinal fluid, and other bodily fluids. The presence of OCBs in serum and CSF suggest systemic Ig synthesis. CSF samples have OCBs in serum that are similar to each other. OCBs in serum and CSF have extra bands in CSF, suggesting intrathecal and systemic Ig synthesis.
GAPDH has been shown to regulate gene expression in endothelial-cell cells. GAPDH expression can also be hypoxia-dependent and cell-specific. GAPDH expression can be found in other cells such as fibroblasts to a lesser degree.
Cells are best able to assess the effects miR-644a 48 hours after transfection with a reagent that contains phosphatase inhibitors as well as protease inhibitions. Bradford's protein test was used to determine the level of protein in the cell lysate. The 2ug proteins were resolved on NuPAGE 4-12% Bis Tris gels and transferred onto nitrocellulose membranes.
Based on their Cp values, several genes were identified to be invariable. The Cp value represents the PCR cycle at which the fluorescent signal crosses the threshold. Publicly available software tools were used to assess the stability of these genes.
CGNs' growth is a valuable model of neurobiology. Neuronal cell lines are useful for studying CGNs. However, they are derived primarily from neuronal tumors. SK-N-SH cell-line was derived from a metastatic, bone tumor biopsy. Primary cultures, by contrast, are non-tumorogenic and more likely not to exhibit neuronal characteristics in vivo.
It is well-known that stress can cause epileptic seizure. Stress can trigger seizures due to the release of dopamine. Yoga, meditation, biofeedback, and deep breathing exercises can reduce stress and lead to healthier brain activity. Additionally, exercise is essential for epilepsy patients and should be done at least 30 minutes five days a week. It is important to disclose any epilepsy to your doctor before you take a medication. Anti-seizure medications can be affected by certain medications. Side effects of other drugs, including antihistamines stimulants and antidepressants may cause side effect and interfere with antiseizure drug.
Although the cause of epilepsy remains unknown, it is typically diagnosed after two seizures. Different brain regions are responsible for different symptoms. For example, the right half controls the left side of the body and the left half controls the right. A seizure that originates from the right side might cause the left arm to jerk. A seizure originating from the right side may cause the left thumb to move and the left hand shake.
The age at which epilepsy begins varies widely. About half of all epilepsy cases are undiagnosed. Children may experience seizures due to a brain defect or trauma. In young adults, the most common known cause is a head injury. For older adults and people in their middle years, strokes or degenerative diseases are the most common causes. Sometimes seizures don't start until after the brain injury.
Myoclonic seizures result in repeated muscle movements, which can affect the face, arms or upper body. The seizures last for less than five minutes. They can cause loss or injury to the brain and/or lead to a fall. A patient suffering from a tonic seizure might also have difficulty controlling their muscles. This can lead to a fall, or even injury. Before deciding on treatment, it's best to consult your doctor.
PMID: 9675132 by Morita R., et al. JH8, a gene highly homologous to the mouse jerky gene, maps to the region for childhood absence epilepsy on 8q24.