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- Table of Contents
Facts about Interleukin-2 receptor subunit beta.
Receptor for interleukin-2.
This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2..
Human | |
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Gene Name: | IL2RB |
Uniprot: | P14784 |
Entrez: | 3560 |
Belongs to: |
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type I cytokine receptor family |
CD122 antigen; CD122; high affinity IL-2 receptor beta subunit; High affinity IL-2 receptor subunit beta; IL-15 R beta; IL-2 R beta; IL-2 receptor subunit beta; IL2R beta; IL-2R subunit beta; IL2RB; IL-2Rb; interleukin 15 receptor, beta; interleukin 2 receptor, beta; interleukin-2 receptor subunit beta; P70-75; p75
Mass (kDA):
61.117 kDA
Human | |
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Location: | 22q12.3 |
Sequence: | 22; NC_000022.11 (37125838..37175118, complement) |
Cell membrane; Single-pass type I membrane protein.
PMID: 2785715 by Hatakeyama M., et al. Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
PMID: 8648694 by Mulloy J.C., et al. The human T-cell leukemia/lymphotropic virus type 1 p12I proteins bind the interleukin-2 receptor beta and gammac chains and affects their expression on the cell surface.