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IL1RL1 Antibodies
AND IL1RL1 ELISA kits, IL1RL1 Proteins
Many biological assays use antibodies to detect IL1RL1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IL1RL1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IL1RL1 antibodies...
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IL1RL1 Infographic by Boster Bio
All IL1RL1 Products
Product
Figures
Specificity
Applications
Price
Human IL-1 RL1 / ST2 ELISA Kit PicoKine®
3 Citations 8 Q&As
Human
ELISA
$499
Cat # EK1116
96 wells/kit, with removable strips.
Cat # EK1116
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # EK1180
96 wells/kit, with removable strips.
Cat # EK1180
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # FEK1116
96 wells/kit, with removable strips.
Cat # FEK1116
96 wells/kit, with removable strips.
IL1RL1 Overview
Facts about Interleukin-1 receptor-like 1.
Interleukin-1 receptor-like 1 (IL1RL1)
Receptor for interleukin-33 (IL-33); signaling requires institution of the coreceptor IL1RAP. Its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8.
Possibly involved in assistant T-cell function. .
Gene Information
| Human | |
|---|---|
| Gene Name: | IL1RL1 |
| Uniprot: | Q01638 |
| Entrez: | 9173 |
Family
| Belongs to: |
|---|
| interleukin-1 receptor family |
Alternative Names
DER4; DER4ST2growth stimulation-expressed; Fit-1; IL-1 R4; IL1R4; IL-1R4; IL-1RL1; IL-33 R; IL33R; IL-33R; interleukin 1 receptor-like 1; interleukin 1 receptor-related protein; interleukin-1 receptor-like 1; Ly84; MGC32623; Protein ST2; ST2; ST2L; ST2V; T1; T1homolog of mouse growth stimulation-expressed
Molecular Weight
Mass (kDA):
63.358 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q12.1 |
| Sequence: | 2; NC_000002.12 (102311502..102352367) |
Tissue Specificity
Highly expressed in kidney, lung, placenta, stomach, skeletal muscle, colon and small intestine. Isoform A is prevalently expressed in the lung, testis, placenta, stomach and colon. Isoform B is more abundant in the brain, kidney and the liver. Isoform C is not detected in brain, heart, liver, kidney and skeletal muscle. Expressed on T-cells in fibrotic liver; at protein level. Overexpressed in fibrotic and cirrhotic liver.
Subcellular Localizations
[Isoform C]: Cell membrane.; [Isoform B]: Secreted.; Cell membrane; Single-pass type I membrane protein.
Diseases
- Inflammation
- Asthma
- Heart Failure
- Myocardial Infarction
- Infarction
- Autoimmune Reaction
- Inflammatory Response
- Arthritis
- Pneumonia
- Rheumatoid Arthritis
- Lung Diseases
- Fibrosis
- Neoplasms
Interacting Proteins
- CLEC7A
- IL33
Pathways
- Pathogenesis
- Cytokine Production
- Secretion
- Immune Response
- Inflammatory Response
- Cell Activation
- Cell Proliferation
- Localization
- Angiogenesis
- Sensitization
- Glomerular Filtration
- T Cell Activation
- Hypersensitivity
PTMs
- Phosphorylation
- Glycosylation
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IL1RL1
bosterbio.com/bosterbio-gene-info-cards/IL1RL1
References
PMID: 1482686 by Tominaga S., et al. Nucleotide sequence of a complementary DNA for human ST2.
PMID: 10527832 by Tominaga S., et al. Presence and expression of a novel variant form of ST2 gene product in human leukemic cell line UT-7/GM.
3 Publications of Boster IL1RL1 Antibodies & ELISA Kits
- PubMed ID: 10.3906/sag-2007-17, Assessment of ST2 and Reg3a levels in patients with acute graft-versus-host dise...
- PubMed ID: 10.1186/s12872-020-01493-2, Comparison of predictive value of NT-proBNP, sST2 and MMPs in heart failure pati...
- PubMed ID: 28614418, Gungor O, Unal HU, Guclu A, Gezer M, Eyileten T, Guzel FB, Altunoren O, Erken E,...
*More publications can be found for each product on its corresponding product page