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Interleukin-17 receptor C Antibodies
AND IL17RC ELISA kits, Interleukin-17 receptor C Proteins
Many biological assays use antibodies to detect Interleukin-17 receptor C, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Interleukin-17 receptor C in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Interleukin-17 receptor C antibodies...
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IL17RC Infographic by Boster Bio
All IL17RC Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK0984
96 wells/kit, with removable strips.
Cat # EK0984
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # EK1181
96 wells/kit, with removable strips.
Cat # EK1181
96 wells/kit, with removable strips.
IL17RC Overview
Facts about Interleukin-17 receptor C.
Interleukin-17 receptor C (IL17RC)
Receptor for IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RA (PubMed:16785495).
Receptor for the heterodimer formed by IL17A and IL17B as part of a heterodimeric complex with IL17RA (PubMed:18684971).Has also been shown to be the cognate receptor for IL17F and to bind IL17A with high affinity with no need for IL17RA (PubMed:17911633). Activation of IL17RC contributes to induction of expression of inflammatory chemokines and cytokines like CXCL1 (PubMed:16785495).
Gene Information
| Human | |
|---|---|
| Gene Name: | IL17RC |
| Uniprot: | Q8NAC3 |
| Entrez: | 84818 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
FLJ95963; FLJ96005; IL-17 RC; IL-17 receptor C; IL-17 RL; IL17F receptor; IL17RC; IL-17RC; IL17Rhom; IL17RL; IL-17RL; IL17-RL; interleukin 17 receptor C; interleukin-17 receptor C; Interleukin-17 receptor homolog; Interleukin-17 receptor-like protein; MGC10763; zcytoR14
Molecular Weight
Mass (kDA):
86.24 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3p25.3|3p25.3-p24.1 |
| Sequence: | 3; NC_000003.12 (9917074..9933627) |
Tissue Specificity
Expressed in prostate, skeletal muscle, kidney and placenta (at protein level) (PubMed:11706037). Expressed in brain, cartilage, colon, heart, intestine, kidney, liver, lung, muscle, placenta, and prostate (PubMed:11706037). Also detected in thyroid, trachea and adrenal gland (PubMed:17911633). Low expression in thymus and leukocytes (PubMed:11706037).
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein. Soluble isoforms may be produced.
Diseases
- Malignant Neoplasms
- Inflammation
- Rheumatoid Arthritis
- Arthritis
- Prostatic Neoplasms
- Autoimmune Reaction
- Malignant Neoplasm Of Prostate
- Neoplasms, Hormone-dependent
- Neoplasms
- Adenocarcinoma
- Autoimmune Diseases
- Crohn Disease
Pathways
- Secretion
- Pathogenesis
- Immune Response
- Intracellular Signal Transduction
- Rna Interference
- Chemokine Production
- Mitosis
- Dna Methylation
- Localization
- Cell Cycle Arrest
- Rna Splicing
- Methylation
- Chemotaxis
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IL17RC
bosterbio.com/bosterbio-gene-info-cards/IL17RC
References
PMID: 17911633 by Kuestner R.E., et al. Identification of the IL-17 receptor related molecule IL-17RC as the receptor for IL-17F.
PMID: 11706037 by Haudenschild D., et al. Soluble and transmembrane isoforms of novel interleukin-17 receptor- like protein by RNA splicing and expression in prostate cancer.