ITPR2 Antibodies

AND ITPR2 ELISA kits, ITPR2 Proteins

Many biological assays use antibodies to detect ITPR2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ITPR2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ITPR2 antibodies...

We validate the specificity of these antibodies to ITPR2 by testing them on tissues known to express ITPR2 positively and negatively. Browse below to find the ITPR2 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CBLIF Next: IVD

ITPR2 Infographic by Boster Bio

All ITPR2 Products

Product

Figures

Specificity

Applications

Price

ITPR2 Overview

Facts about Inositol 1,4,5-trisphosphate receptor type 2.

Inositol 1,4,5-trisphosphate receptor type 2 (ITPR2)

Receptor for inositol 1,4,5-trisphosphate, another messenger that mediates the release of intracellular calcium. This release is regulated by cAMP both dependently and independently of PKA (By similarity).

Gene Information

Human
Gene Name:	ITPR2
Uniprot:	Q14571
Entrez:	3709

Family

Belongs to:

InsP3 receptor family

Alternative Names

inositol 14,5-triphosphate receptor, type 2; inositol 14,5-trisphosphate receptor type 2; insP3R2; IP3 receptor isoform 2; IP3 receptor; IP3R 2; IP3R2; Type 2 inositol 14,5-trisphosphate receptor; Type 2 InsP3 receptor

Molecular Weight

Mass (kDA):
308.064 kDA

Genomic Context


Human

Location:	12p11.23
Sequence:	12; NC_000012.12 (26335352..26833197, complement)

Tissue Specificity

Isoform Short is found in skeletal muscle and heart.

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Diseases

Amyotrophic Lateral Sclerosis
Malignant Neoplasms
Sclerosis
Primary Lateral Sclerosis
Carcinoma
Lymphoma
Inflammation
Respiration Disorders
Lung Diseases
Neoplasms
Dysequilibrium Syndrome
Stress, Psychological
Nerve Degeneration

Tissue Adhesions
Cholangiocarcinoma
Disease Of Adrenal Medulla
Hepatitis B
Kidney Neoplasm
Myeloid Leukemia
Chlamydia Infections

Pathways

Localization
Cell Adhesion
Secretion
Transport
Cell Migration
Programmed Cell Death
Cellular Homeostasis
Fertilization
Aging
Muscle Contraction
Regulation Of Gene Expression
Tissue Development
Cell Cycle

Metabolic Process
Interleukin-2 Production
Smooth Muscle Contraction
Intracellular Signal Transduction
Bmp Signaling Pathway
Rna Splicing
Coagulation

PTMs

Phosphorylation

Acetylation

Research Areas

Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ITPR2

References

PMID: 8081734 by Yamamoto-Hino M., et al. Cloning and characterization of human type 2 and type 3 inositol 1,4,5-trisphosphate receptors.

PMID: 9729462 by Futatsugi A., et al. Muscle-specific mRNA isoform encodes a protein composed mainly of the N-terminal 175 residues of type 2 Ins(1,4,5)P3 receptor.