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Integrin alpha-X Antibodies
AND ITGAX ELISA kits, Integrin alpha-X Proteins
Many biological assays use antibodies to detect Integrin alpha-X, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Integrin alpha-X in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Integrin alpha-X antibodies...
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ITGAX Infographic by Boster Bio
All ITGAX Products
Product
Figures
Specificity
Applications
Price
Human
Flow Cytometry, IF, Functional Assay
$486
Cat # M00357
100ug/vial
Cat # M00357
100ug/vial
Human
IP, IF, IHC, ICC, WB
$370
Cat # M00357-1
100 μl
Cat # M00357-1
100 μl
Anti-CD11c/ITGAX Antibody Picoband®
2 Citations 17 Q&As
Human, Mouse
ELISA, IHC, WB
$370
Cat # A00357-1
100 μg/vial
Cat # A00357-1
100 μg/vial
Cynomolgus monkey, Human, Baboon, Rhesus monkey
Flow Cytometry
$147
Cat # FC00357
100ug, 500ug
Cat # FC00357
100ug, 500ug
Cynomolgus monkey, Human, Baboon, Rhesus monkey
Flow Cytometry
$299
Cat # FC00357-PE
100 tests, 200 tests
Cat # FC00357-PE
100 tests, 200 tests
Anti-CD11c/Itgax Antibody Picoband®
3 Citations
Mouse, Rat
ELISA, IHC, WB
$370
Cat # A00357-3
100 μg/vial
Cat # A00357-3
100 μg/vial
ITGAX Overview
Facts about Integrin alpha-X.
Integrin alpha-X (ITGAX)
Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen.
It mediates cell-cell interaction during inflammatory reactions. It is especially important in monocyte adhesion and chemotaxis.
Gene Information
| Human | |
|---|---|
| Gene Name: | ITGAX |
| Uniprot: | P20702 |
| Entrez: | 3687 |
Family
| Belongs to: |
|---|
| integrin alpha chain family |
Alternative Names
95 alpha chain; 95; 95, alpha subunit; CD11 antigen-like family member C; CD11c antigen; CD11c; CD11Cleu M5, alpha subunit; Integrin alpha X; integrin alpha-X; integrin, alpha X (antigen CD11C (p150), alpha polypeptide); integrin, alpha X (complement component 3 receptor 4 subunit); ITGAX; Leu M5; Leukocyte adhesion glycoprotein p150; Leukocyte adhesion receptor p150; leukocyte surface antigen p150; myeloid membrane antigen, alpha subunit; p150 95 integrin alpha chain; p150,95 alpha; SLEB6
Molecular Weight
Mass (kDA):
127.829 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 16p11.2 |
| Sequence: | 16; NC_000016.10 (31355167..31382999) |
Tissue Specificity
Predominantly expressed in monocytes and granulocytes.
Subcellular Localizations
Membrane; Single-pass type I membrane protein.
Diseases
- Inflammation
- Tissue Adhesions
- Neoplasms
- Lupus Erythematosus, Systemic
- Brain Injuries
- Hypertrophy
- Diphtheria
- Collecting Duct Carcinoma Of The Kidney
- Autoimmunity
- Sclerosis
- Neoplasm Metastasis
- Hamman-rich Syndrome
- Melanoma
Interacting Proteins
- ITGB2
Pathways
- Neurogenesis
- Cell Adhesion
- Cell Activation
- Muscle Cell Migration
- Cell Migration
- Smooth Muscle Cell Migration
- Fertilization
- Aging
- T Cell Activation
- Localization
PTMs
- Disulfide bond
Research Areas
- Dendritic Cell Markers
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ITGAX
bosterbio.com/bosterbio-gene-info-cards/ITGAX
References
PMID: 3327687 by Corbi A.L., et al. cDNA cloning and complete primary structure of the alpha subunit of a leukocyte adhesion glycoprotein, p150,95.
PMID: 2303426 by Corbi A.L., et al. Genomic structure of an integrin alpha subunit, the leukocyte p150,95 molecule.
4 Publications of Boster Integrin alpha-X Antibodies & ELISA Kits
- PubMed ID: PMID:25691929, Expressions of CD11a, CD11b, and CD11c integrin proteins in rats with myocardial...
- PubMed ID: 10.1016/j.tranon.2016.12.002, Immunotherapy with Dendritic Cells Modified with Tumor-Associated Antigen Gene D...
- PubMed ID: 25691929, Mu L, Jing C, Guo Z. Iran J Basic Med Sci. 2014 Nov;17(11):874-8. Expressions Of...
- PubMed ID: 23346371, Huang J, Zhu C, Zhang P, Zhu Q, Liu Y, Zhu Z, Wang M, Li W, Yang G, Dong N, Liu ...
*More publications can be found for each product on its corresponding product page