Isthmin-2 Antibodies

AND ISM2 ELISA kits, Isthmin-2 Proteins

Many biological assays use antibodies to detect Isthmin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Isthmin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Isthmin-2 antibodies...

We validate the specificity of these antibodies to Isthmin-2 by testing them on tissues known to express ISM2 positively and negatively. Browse below to find the ISM2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ISM2 Infographic by Boster Bio

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ISM2 (NM_182509) Human Over-expression Lysate

Human

$628
Cat # LS145501
100 µg

ISM2 Overview

Facts about Isthmin-2.

ISM2 3D structure. Source: alphafold

Isthmin-2 (ISM2)

Gene Information

Human
Gene Name:	ISM2
Uniprot:	Q6H9L7
Entrez:	145501

Family

Belongs to:

isthmin family

Alternative Names

DKFZp686E0215; FLJ32147; isthmin 2 homolog (zebrafish); PSEC0137; thrombospondin and AMOP domain-containing isthmin-like protein 1; thrombospondin type-1 domain-containing protein 3; thrombospondin, type I domain-containing 3; THSD3; type I, domain containing 3

Molecular Weight

Mass (kDA):
63.906 kDA

Genomic Context


Human

Location:	14q24.3
Sequence:	14; NC_000014.9 (77474394..77498816, complement)

Tissue Specificity

Expressed at high levels in the placenta and at moderate levels in the pancreas, kidney, heart, liver, lung, brain and skeletal muscle.

Subcellular Localizations

Secreted.

Diseases

Multiple Endocrine Neoplasia
Mycoplasma Pneumonia
Tumor Angiogenesis
Nervousness
Ectopic Pregnancy
Arrhythmogenic Right Ventricular Dysplasia
Shwachman Syndrome

Tissue Adhesions
Subfertility

Pathways

Blastocyst Formation
Fertilization
Mating
Embryo Development
Cell Adhesion
Angiogenesis

PTMs

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ISM2

References

PMID: 15194193 by Rossi V., et al. TAIL1: an isthmin-like gene, containing type 1 thrombospondin-repeat and AMOP domain, mapped to ARVD1 critical region.