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- Table of Contents
Facts about Interferon regulatory factor 2.
Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth.
Human | |
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Gene Name: | IRF2 |
Uniprot: | P14316 |
Entrez: | 3660 |
Belongs to: |
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IRF family |
DKFZp686F0244; interferon regulatory factor 2; IRF2; IRF-2
Mass (kDA):
39.354 kDA
Human | |
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Location: | 4q35.1 |
Sequence: | 4; NC_000004.12 (184382741..184474580, complement) |
Expressed throughout the epithelium of the colon. Also expressed in lamina propria.
Nucleus.
PMID: 2813069 by Itoh S., et al. Sequence of a cDNA coding for human IRF-2.
PMID: 8106512 by Cha Y., et al. Human interferon regulatory factor 2 gene. Intron-exon organization and functional analysis of 5'-flanking region.