INPP5A Antibodies

AND INPP5A ELISA kits, INPP5A Proteins

Many biological assays use antibodies to detect INPP5A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with INPP5A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop INPP5A antibodies...

We validate the specificity of these antibodies to INPP5A by testing them on tissues known to express INPP5A positively and negatively. Browse below to find the INPP5A antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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INPP5A Infographic by Boster Bio

All INPP5A Products

Product

Figures

Specificity

Applications

Price

Anti-INPP5A Antibody

Mouse, Rat

$405
Cat # A11404
100ul

INPP5A (NM_005539) Human Over-expression Lysate

Human

$628
Cat # LS003632
100 µg

INPP5A Overview

Facts about Inositol polyphosphate-5-phosphatase A.

INPP5A 3D structure. Source: alphafold

Inositol polyphosphate-5-phosphatase A (INPP5A)

Important isoenzyme hydrolyzing the calcium-mobilizing second messenger Ins(1,4,5)P3, this is a signal-terminating reaction. .

Gene Information

Human
Gene Name:	INPP5A
Uniprot:	Q14642
Entrez:	3632

Family

Belongs to:

inositol 1,4,5-trisphosphate 5-phosphatase type I family

Alternative Names

43 kDa inositol polyphosphate 5-phophatase; CTCL tumor antigen HD-CL-02,5PTASE; DKFZp434A1721; EC 3.1.3.56; inositol polyphosphate-5-phosphatase, 40kD; inositol polyphosphate-5-phosphatase, 40kDa; inositol trisphosphate-5-phosphatase, 40kD; InsP3 5-phosphatase; MGC116947,5PTase; MGC116949; type I inositol-14,5-trisphosphate 5-phophatase; type I inositol-14,5-trisphosphate 5-phosphatase

Molecular Weight

Mass (kDA):
47.82 kDA

Genomic Context


Human

Location:	10q26.3
Sequence:	10; NC_000010.11 (132537784..132783480)

Tissue Specificity

Brain; high level in Purkinje cells.

Subcellular Localizations

Cell membrane; Lipid-anchor.

Diseases

Neoplasms
Malignant Squamous Cell Neoplasm
Skin Neoplasms
Carcinoma
Keratosis
Neoplasm Metastasis
Glioblastoma Multiforme
Spinocerebellar Ataxia Type 2
Squamous Cell Carcinoma Of Skin
Neurodegenerative Disorders
Ataxia
Oculocerebrorenal Syndrome

Glioma
Glioblastoma
Brain Neoplasms
Abnormal Coordination
Colorectal Neoplasms
Actinic Keratosis
Ataxia, Spinocerebellar

Interacting Proteins

PLEK

Pathways

Transport
Rna Processing
Pathogenesis

PTMs

Phosphorylation

Research Areas

Protein Phosphatase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/INPP5A

References

PMID: 8013665 by de Smedt F., et al. Cloning and expression of human brain type I inositol 1,4,5- trisphosphate 5-phosphatase. High levels of mRNA in cerebellar Purkinje cells.

PMID: 8006039 by Laxminarayan K.M., et al. Characterization of a cDNA encoding the 43-kDa membrane-associated inositol-polyphosphate 5-phosphatase.