INO80 Antibodies

AND INO80 ELISA kits, INO80 Proteins

Many biological assays use antibodies to detect INO80, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with INO80 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop INO80 antibodies...

We validate the specificity of these antibodies to INO80 by testing them on tissues known to express INO80 positively and negatively. Browse below to find the INO80 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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INO80 Infographic by Boster Bio

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INO80 Overview

Facts about Chromatin-remodeling ATPase INO80.

INO80 3D structure. Source: alphafold

Chromatin-remodeling ATPase INO80 (INO80)

ATPase component of the chromatin remodeling INO80 complex that is involved in transcriptional regulation, DNA replication and DNA repair (PubMed:16230350, PubMed:16298340, PubMed:17721549, PubMed:20855601, PubMed:20237820). Binds DNA (PubMed:16298340, PubMed:21303910).

As part of the INO80 complex, remodels chromatin by shifting nucleosomes (PubMed:16230350, PubMed:21303910). Regulates transcription upon recruitment by YY1 to YY1-activated genes, where it acts as an essential coactivator (PubMed:17721549).

Gene Information

Human
Gene Name:	INO80
Uniprot:	Q9ULG1
Entrez:	54617

Family

Belongs to:

SNF2/RAD54 helicase family

Alternative Names

EC 3.6.1; EC 3.6.1.23; EC 3.6.4.12; hINO80INO80 complex subunit A; homolog of yeast INO80; INO80 complex homolog 1 (S. cerevisiae); INO80 homolog (S. cerevisiae); Ino80; INO80A; INOC1putative DNA helicase INO80 complex homolog 1; KIAA1259

Molecular Weight

Mass (kDA):
176.753 kDA

Genomic Context


Human

Location:	15q15.1
Sequence:	15; NC_000015.10 (40978880..41117778, complement)

Tissue Specificity

According to PubMed:10574462, widely expressed. According to PubMed:16298340, specifically expressed in brain, liver and pancreas.

Subcellular Localizations

Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome. Localizes to the cytoplasm in quiescent cell (PubMed:20237820). Associates with spindle microtubules during mitosis (PubMed:20237820). Colocalizes with PCNA at replication forks during S-phase (PubMed:20237820). Recruited to DNA damage sites in a ACTR8-dependent manner (PubMed:20971067).