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- Table of Contents
Facts about SOSS complex subunit C.
Required for efficient homologous recombination- dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. .
Human | |
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Gene Name: | INIP |
Uniprot: | Q9NRY2 |
Entrez: | 58493 |
Belongs to: |
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SOSS-C family |
chromosome 9 open reading frame 80; HSPC043; hSSB-interacting protein 1; hSSBIP1; minute INTS3/hSSB-associated element; MISE; Sensor of single-strand DNA complex subunit C; Sensor of ssDNA subunit C; Single-stranded DNA-binding protein-interacting protein 1; SOSS complex subunit C; SOSSC; SOSS-C; SSB-interacting protein 1; SSBIP1
Mass (kDA):
11.425 kDA
Human | |
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Location: | 9q32 |
Sequence: | 9; NC_000009.12 (112683926..112718117, complement) |
Nucleus. Localizes to nuclear foci following DNA damage.
PMID: 19605351 by Li Y., et al. hSSB1 and hSSB2 form similar multiprotein complexes that participate in DNA damage response.
PMID: 19683501 by Huang J., et al. SOSS complexes participate in the maintenance of genomic stability.