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IL4R Antibodies
AND IL4R ELISA kits, IL4R Proteins
Many biological assays use antibodies to detect IL4R, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IL4R in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IL4R antibodies...
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IL4R Infographic by Boster Bio
All IL4R Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
ELISA
$480
Cat # EKC1300
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1300
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse
ELISA
$540
Cat # EKC2299
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2299
1 kit, containing two 96-well plates and all necessary reagents
Human
ELISA
$499
Cat # EK2092
96 wells/kit, with removable strips.
Cat # EK2092
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # EK2093
96 wells/kit, with removable strips.
Cat # EK2093
96 wells/kit, with removable strips.
Human, Mouse
ELISA, IF, IHC-P, WB
$380
Cat # A00807Y497
100ul
Cat # A00807Y497
100ul
IL4R Overview
Facts about Interleukin-4 receptor subunit alpha.
Interleukin-4 receptor subunit alpha (IL4R)
Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway.
The IL4 response is included in promoting Th2 differentiation. The IL4/IL13 responses are included in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation.
Gene Information
| Human | |
|---|---|
| Gene Name: | IL4R |
| Uniprot: | P24394 |
| Entrez: | 3566 |
Family
| Belongs to: |
|---|
| type I cytokine receptor family |
Alternative Names
CD124 antigen; CD124; IL-4 R alpha; IL-4 receptor subunit alpha; IL4R alpha; IL-4R alpha; IL-4R subunit alpha; IL4R; IL-4Ra; IL4RACD124; IL-4R-alpha; interleukin 4 receptor; interleukin-4 receptor alpha chain; interleukin-4 receptor subunit alpha
Molecular Weight
Mass (kDA):
89.658 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 16p12.1 |
| Sequence: | 16; NC_000016.10 (27313668..27364778) |
Tissue Specificity
Isoform 1 and isoform 2 are highly expressed in activated T-cells.
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.
Diseases
- Asthma
- Inflammation
- Neoplasms
- Malignant Neoplasms
- Allergy
- Dysequilibrium Syndrome
- Allergic Asthma
- Lymphoma
- Diabetes Mellitus
- Diabetes Mellitus, Insulin-dependent
- Arthritis
- Rheumatoid Arthritis
- Brain Neoplasms
Interacting Proteins
- IL4
- STAT6
Pathways
- Pathogenesis
- Immune Response
- Cell Differentiation
- Innate Immune Response
- Angiogenesis
- Secretion
- Inflammatory Response
- Sensitization
- Cell Proliferation
- Dna Methylation
- Methylation
- B Cell Differentiation
- Cell Adhesion
PTMs
- Phosphorylation
- Reduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IL4R
bosterbio.com/bosterbio-gene-info-cards/IL4R
References
PMID: 2307934 by Idzerda R.L., et al. Human interleukin 4 receptor confers biological responsiveness and defines a novel receptor superfamily.
PMID: 2278997 by Galizzi J.-P., et al. Molecular cloning of a cDNA encoding the human interleukin 4 receptor.