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- Table of Contents
Facts about Interleukin-34.
Plays an essential role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling through CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1 (By similarity).
Mouse | |
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Gene Name: | Il34 |
Uniprot: | Q8R1R4 |
Entrez: | 76527 |
Belongs to: |
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IL-34 family |
C16orf77; IL34; IL-34; interleukin 34
Mass (kDA):
26.764 kDA
Mouse | |
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Location: | 8|8 E1 |
Sequence: | 8; |
PMID: 18467591 by Lin H., et al. Discovery of a cytokine and its receptor by functional screening of the extracellular proteome.