IGF2BP1 Antibodies

AND IGF2BP1 ELISA kits, IGF2BP1 Proteins

Many biological assays use antibodies to detect IGF2BP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IGF2BP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IGF2BP1 antibodies...

We validate the specificity of these antibodies to IGF2BP1 by testing them on tissues known to express IGF2BP1 positively and negatively. Browse below to find the IGF2BP1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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IGF2BP1 Infographic by Boster Bio

All IGF2BP1 Products

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Product

Figures

Specificity

Applications

Price

Anti-IGF2BP1 Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A02007
100ul

Anti-IGF2BP1 Antibody (C-term)

Human, Mouse

Flow Cytometry, IHC-P, WB

$299
Cat # A02007-1
80 µl

Anti-IMPI/IGF2BP1 Antibody Picoband®

1 Citations

Human

ELISA, Flow Cytometry, WB

$370
Cat # A02007-2
100 μg/vial

IGF2BP1 (NM_006546) Human Over-expression Lysate

Human

$960
Cat # LS010642
100 µg

IGF2BP1 Overview

Facts about Insulin-like growth factor 2 mRNA-binding protein 1.

IGF2BP1 3D structure. Source: alphafold

Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1)

RNA-binding factor that recruits target transcripts into cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage.

It also modulates the speed and location where target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Plays a direct role in the transport and translation of transcripts necessary for axonal regeneration in adult sensory neurons (By similarity).

Gene Information

Human
Gene Name:	IGF2BP1
Uniprot:	Q9NZI8
Entrez:	10642

Family

Belongs to:

RRM IMP/VICKZ family

Alternative Names

Coding region determinant-binding protein; CRD-BP; CRDBPIGF-II mRNA-binding protein 1; IGF II mRNA binding protein 1; IMP1; IMP-1ZBP-1; insulin-like growth factor 2 mRNA binding protein 1; insulin-like growth factor 2 mRNA-binding protein 1; VICKZ family member 1; VICKZ1; ZBP1IGF2 mRNA-binding protein 1; Zip code-binding protein 1; Zipcode-binding protein 1

Molecular Weight

Mass (kDA):
63.481 kDA

Genomic Context


Human

Location:	17q21.32
Sequence:	17; NC_000017.11 (48997385..49056145)

Tissue Specificity

Mainly expressed in the embryo, including in fetal liver, fetal lung, fetal kidney, fetal thymus (at protein level). Also expressed follicles of ovary, as well as in gonocytes of testis, spermatogonia, semen, oocytes and placenta (at protein level). Expressed in various cancers, including testis and lung cancers (at protein level), as well as kidney, prostate and trachea cancers.

Subcellular Localizations

Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Cell projection, lamellipodium. Cell projection, dendrite. Cell projection, dendritic spine. Cell projection, growth cone. Cell projection, filopodium. Cell projection, axon. In the nucleus, located in discrete foci, coinciding with the sites of ACTB transcription (By similarity). In the cytoplasm, localizes in cytoplasmic mRNP granules. Colocalizes with microtubules in growth cone filopodia and along neurites in neuronal cells (By similarity). Cytoplasmic colocalization with ACTB mRNA is partially lost at the cell periphery, suggesting releas

Diseases

Malignant Neoplasms
Neoplasms
Neoplasm Metastasis
Cell Transformation, Neoplastic
Malignant Paraganglionic Neoplasm
Tissue Adhesions
Mutation Abnormality
Oncogene Activation Process
Intracranial Neoplasm
Endometrial Polyp
Malignant Neoplasm Of Lung
Immunologic Deficiency Syndromes

Myopathy
Metabolic Syndrome X
Exanthema
Meningeal Neoplasms
Meningioma
Leukaemia Recurrent
Congenital Absence

Interacting Proteins

Cbx7
STAU1

Pathways

Translation
Cell Migration
Dna Methylation
Localization
Methylation
Transport
Cell Adhesion
Cell Proliferation
Cell Aging
Aging
Histone Modification
Virulence
Senescence

Tooth Eruption
Organ Development
Mrna Stabilization
Vulval Development
Menarche
Wound Healing
Iron-sulfur Cluster Assembly

PTMs

Methylation

Phosphorylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IGF2BP1

References

PMID: 9891060 by Nielsen J., et al. A family of insulin-like growth factor II mRNA-binding proteins represses translation in late development.

PMID: 16356927 by Patel G.P., et al. The autoregulatory translational control element of poly(A)-binding protein mRNA forms a heteromeric ribonucleoprotein complex.

1 Publications of Boster IGF2BP1 Antibodies & ELISA Kits

PubMed ID: 10.3748/wjg.v25.i40.6063, Insulin-like growth factor 2 mRNA-binding protein 1 promotes cell proliferation ...

*More publications can be found for each product on its corresponding product page