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- Table of Contents
Facts about Interferon kappa.
Activates the interferon- stimulated response element signaling pathway. It's able to directly modulate cytokine release from monocytes and dendritic cells.
Human | |
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Gene Name: | IFNK |
Uniprot: | Q9P0W0 |
Entrez: | 56832 |
Belongs to: |
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alpha/beta interferon family |
IFNK; IFNkappa; IFN-kappa
Mass (kDA):
25.218 kDA
Human | |
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Location: | 9p21.2 |
Sequence: | 9; NC_000009.12 (27524314..27526498) |
Expressed in keratinocytes, monocytes and in resting dendritic cells.
Secreted.
PMID: 11514542 by LaFleur D.W., et al. Interferon-kappa, a novel type I interferon expressed in human keratinocytes.
PMID: 12391192 by Nardelli B., et al. Regulatory effect of IFN-kappa, a novel type I IFN, on cytokine production by cells of the innate immune system.