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- Table of Contents
Facts about Gamma-interferon-inducible lysosomal thiol reductase.
Plays an important role in antigen processing. Facilitates the generation of MHC class II- restricted epitodes from disulfide bond-containing antigen by the endocytic reduction of disulfide bonds (By similarity).
Human | |
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Gene Name: | IFI30 |
Uniprot: | P13284 |
Entrez: | 10437 |
Belongs to: |
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GILT family |
EC 1.8; Gamma-interferon-inducible protein IP-30; GILT; GILTgamma-interferon-inducible lysosomal thiol reductase; IFI30; IFI-30; interferon, gamma-inducible protein 30; IP30; IP30interferon gamma-inducible protein 30 preproprotein; Legumaturain; MGC32056
Mass (kDA):
27.964 kDA
Human | |
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Location: | 19p13.11 |
Sequence: | 19; NC_000019.10 (18173813..18178117) |
Secreted. Lysosome.
PMID: 3136170 by Luster A.D., et al. Molecular and biochemical characterization of a novel gamma- interferon-inducible protein.
PMID: 10639150 by Arunachalam B., et al. Enzymatic reduction of disulfide bonds in lysosomes: characterization of a gamma-interferon-inducible lysosomal thiol reductase (GILT).