Homeodomain-only protein Antibodies

AND Hopx ELISA kits, Homeodomain-only protein Proteins

Many biological assays use antibodies to detect Homeodomain-only protein, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Homeodomain-only protein in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Homeodomain-only protein antibodies...

We validate the specificity of these antibodies to Homeodomain-only protein by testing them on tissues known to express Hopx positively and negatively. Browse below to find the Hopx antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Hopx Infographic by Boster Bio

All Hopx Products

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Specificity

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Price

Anti-Homeodomain-only protein HOPX Antibody

Human

ELISA, IF, IHC-P, WB

$449
Cat # A05019
0.1 mg

HOPX (NM_139211) Human Recombinant Protein

$813
Cat # PROTQ9BPY8
20 µg

HOPX (NM_032495) Human Over-expression Lysate

Human

$628
Cat # LS084525
100 µg

Hopx Overview

Facts about Homeodomain-only protein.

Homeodomain-only protein (Hopx)

Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development.

Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (PubMed:12297045, PubMed:12297046).

Gene Information

Mouse
Gene Name:	Hopx
Uniprot:	Q8R1H0
Entrez:	74318

Family

Belongs to:

No superfamily

Alternative Names

CAMEO; HOD; homeodomain-only protein; HOP homeobox; HOPLAGYNECC1OB1SMAP31; Lung cancer-associated Y protein; MGC20820; not expressed in choriocarcinoma clone 1; Not expressed in choriocarcinoma protein 1; odd homeobox 1 protein; Odd homeobox protein 1; TOTO

Molecular Weight

Mass (kDA):
8.282 kDA

Genomic Context


Mouse

Location:	5\|5 C3.3
Sequence:	5;

Tissue Specificity

Expressed in the embryonic and adult heart and in the adult brain, liver, lung, skeletal muscle, intestine and spleen. Throughout embryonic and postnatal development, it is expressed in the myocardium.

Diseases

Malignant Neoplasms
Neoplasms
Cell Invasion
Chronic Inflammation
Inflammation
Colorectal Cancer
Colitis
Malignant Neoplasm Of Stomach
Stomach Neoplasms
Stenosis
Endometrial Neoplasms
Cardiac Hypertrophy

Endometrial Polyp
Neoplasm Invasiveness
Carcinogenesis
Eye Abnormalities
Carcinoma
Leukemia, Myelocytic, Acute
Fibrosarcoma

Pathways

Methylation
Cell Proliferation
Cell Cycle
Cell Differentiation
Dna Hypermethylation
Stem Cell Differentiation
Dna Methylation
Dna Repair
Histone Modification
Regulation Of Gene Expression

Regeneration
Angiogenesis
Wound Healing
Pathogenesis
Rna Interference

PTMs

Methylation
Demethylation

Deacetylation
Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Hopx

References

PMID: 12297045 by Chen F., et al. Hop is an unusual homeobox gene that modulates cardiac development.

PMID: 12297046 by Shin C.H., et al. Modulation of cardiac growth and development by HOP, an unusual homeodomain protein.