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- Table of Contents
Facts about Hyaluronan synthase 2.
This is one of the isozymes catalyzing that response and it is very responsible for the synthesis of high molecular mass hyaluronan. Required for the transition of endocardial cushion cells to mesenchymal cells, a process crucial for heart development.
Human | |
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Gene Name: | HAS2 |
Uniprot: | Q92819 |
Entrez: | 3037 |
Belongs to: |
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NodC/HAS family |
EC 2.4.1.212; HA synthase 2; hyaluronan synthase 2; Hyaluronate synthase 2; Hyaluronic acid synthase 2; MGC126241; MGC126242
Mass (kDA):
63.566 kDA
Human | |
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Location: | 8q24.13 |
Sequence: | 8; NC_000008.11 (121612116..121641440, complement) |
Expressed in fibroblasts.
Membrane; Multi-pass membrane protein.
PMID: 8798477 by Watanabe K., et al. Molecular identification of a putative human hyaluronan synthase.
PMID: 15642402 by Morerio C., et al. PLAG1-HAS2 fusion in lipoblastoma with masked 8q intrachromosomal rearrangement.