HTR3E Antibodies

AND HTR3E ELISA kits, HTR3E Proteins

Many biological assays use antibodies to detect HTR3E, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HTR3E in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HTR3E antibodies...

We validate the specificity of these antibodies to HTR3E by testing them on tissues known to express HTR3E positively and negatively. Browse below to find the HTR3E antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HTR3E Infographic by Boster Bio

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5HT3E (HTR3E) (NM_182589) Human Over-expression Lysate

Human

$960
Cat # LS285242
100 µg

HTR3E Overview

Facts about 5-hydroxytryptamine receptor 3E.

HTR3E 3D structure. Source: alphafold

5-hydroxytryptamine receptor 3E (HTR3E)

This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses.

It is a cation-specific, but otherwise relatively nonselective, ion channel. .

Gene Information

Human
Gene Name:	HTR3E
Uniprot:	A5X5Y0
Entrez:	285242

Family

Belongs to:

ligand-gated ion channel (TC 1.A.9) family

Alternative Names

5-HT3 receptor subunit E splice variant HTR3Ea; 5-HT3c1; 5-HT3c1,5-HT3E; 5HT3E; 5-HT3E; 5-hydroxytryptamine (serotonin) receptor 3, family member E; 5-hydroxytryptamine receptor 3E; HTR3E; MGC120035; MGC120036; serotonin receptor 3E

Molecular Weight

Mass (kDA):
51.438 kDA

Genomic Context


Human

Location:	3q27.1
Sequence:	3; NC_000003.12 (184097064..184106995)

Tissue Specificity

Expressed in adult colon and intestine.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Presumably retained within the endoplasmic reticulum unless complexed with HTR3A.

Diseases

Malignant Neoplasms
Nausea And Vomiting
Irritable Bowel Syndrome
Nausea
Vomiting
Nervousness
Schizophrenia
Chemotherapy-induced Nausea And Vomiting
Neoplasm Metastasis
Pregnancy Complications
Malignant Neoplasm Of Breast
Parkinson Disease

Neoplasms
Stress Disorders, Traumatic
Headache
Pain
Mammary Neoplasms
Diarrhea
Stress, Psychological

Interacting Proteins

HTR3A

Pathways

Pathogenesis

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HTR3E

References

PMID: 12801637 by Niesler B., et al. Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E.

PMID: 14597179 by Karnovsky A.M., et al. A cluster of novel serotonin receptor 3-like genes on human chromosome 3.