HTR3B Antibodies

AND HTR3B ELISA kits, HTR3B Proteins

Many biological assays use antibodies to detect HTR3B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HTR3B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HTR3B antibodies...

We validate the specificity of these antibodies to HTR3B by testing them on tissues known to express HTR3B positively and negatively. Browse below to find the HTR3B antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HTR3B Infographic by Boster Bio

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Anti-5HT3B HTR3B Antibody

Human

ELISA, WB

$380
Cat # A04287
100ul

HTR3B Overview

Facts about 5-hydroxytryptamine receptor 3B.

HTR3B 3D structure. Source: alphafold

5-hydroxytryptamine receptor 3B (HTR3B)

This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses.

It is a cation-specific, but otherwise relatively nonselective, ion channel. .

Gene Information

Human
Gene Name:	HTR3B
Uniprot:	O95264
Entrez:	9177

Family

Belongs to:

ligand-gated ion channel (TC 1.A.9) family

Alternative Names

5HT3B; 5-HT3B; 5-HT3-B; 5-HT3B5-hydroxytryptamine receptor 3B; 5-hydroxytryptamine (serotonin) receptor 3B; 5-hydroxytryptamine 3 receptor B subunit; HTR3B; Serotonin receptor 3B; serotonin-gated ion channel subunit

Molecular Weight

Mass (kDA):
50.292 kDA

Genomic Context


Human

Location:	11q23.2
Sequence:	11; NC_000011.10 (113898923..113949119)

Tissue Specificity

Expressed in the brain cortex, in the caudate nucleus, the hyppocampus, the thalamus and the amygdala. Detected in the kidney and testis as well as in monocytes of the spleen, small and large intestine, uterus, prostate, ovary and placenta.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Presumably retained within the endoplasmic reticulum unless complexed with HTR3A.

Diseases

Nausea
Vomiting
Nausea And Vomiting
Schizophrenia
Malignant Neoplasms
Pain
Mental Disorders
Depressive Disorder
Nervousness
Mood Disorders
Chemotherapy-induced Nausea And Vomiting
Neoplasms

Major Depressive Disorder
Bipolar Disorder
Malignant Neoplasm Of Breast
Mammary Neoplasms
Dysequilibrium Syndrome
Irritable Bowel Syndrome

Pathways

Pathogenesis
Transport
Bioluminescence
Response To Clozapine
Peristalsis
Cognition

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HTR3B

References

PMID: 10521471 by Dubin A.E., et al. The pharmacological and functional characteristics of the serotonin 5-HT(3A) receptor are specifically modified by a 5-HT(3B) receptor subunit.

PMID: 9950429 by Davies P.A., et al. The 5-HT3B subunit is a major determinant of serotonin-receptor function.