This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about 5-hydroxytryptamine receptor 1F.
Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
Human | |
---|---|
Gene Name: | HTR1F |
Uniprot: | P30939 |
Entrez: | 3355 |
Belongs to: |
---|
G-protein coupled receptor 1 family |
5HT1F; 5-HT1F; 5-HT-1F; 5HT6; 5-hydroxytryptamine (serotonin) receptor 1F; HTR1EL; HTR1ELMR77,5-HT1F5-hydroxytryptamine receptor 1F; HTR1F; MR77; Serotonin receptor 1F
Mass (kDA):
41.709 kDA
Human | |
---|---|
Location: | 3p11.2-p11.1 |
Sequence: | 3; NC_000003.12 (87792706..87994856) |
Cell membrane; Multi-pass membrane protein.
PMID: 8384716 by Lovenberg T.W., et al. Molecular cloning and functional expression of 5-HT1E-like rat and human 5-hydroxytryptamine receptor genes.
PMID: 8380639 by Adham N., et al. Cloning of another human serotonin receptor (5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase.