HTR1A Antibodies

AND HTR1A ELISA kits, HTR1A Proteins

Many biological assays use antibodies to detect HTR1A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HTR1A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HTR1A antibodies...

We validate the specificity of these antibodies to HTR1A by testing them on tissues known to express HTR1A positively and negatively. Browse below to find the HTR1A antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CBLIF Next: HTR1D

HTR1A Infographic by Boster Bio

All HTR1A Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-5HT1A Receptor/HTR1A Antibody Picoband®

7 Q&As

Human, Rat

IHC, WB

$370
Cat # PA1647
100 μg/vial

Anti-SR-1A HTR1A Antibody

Human, Mouse, Rat

ELISA, IF, IHC, WB

$380
Cat # A01467
100ul

Anti-HTR1A Antibody (Center)

Human

Flow Cytometry, WB

$299
Cat # A01467-1
80 µl

HTR1A Overview

Facts about 5-hydroxytryptamine receptor 1A.

HTR1A 3D structure. Source: alphafold

5-hydroxytryptamine receptor 1A (HTR1A)

G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances.

Ligand binding causes a conformation change that triggers signaling through guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling through G proteins and mediate activation of alternative signaling pathways.

Gene Information

Human
Gene Name:	HTR1A
Uniprot:	P08908
Entrez:	3350

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

5-HT1a receptor; 5HT1A; 5-HT1A; 5-HT-1A; 5-HT1A5-hydroxytryptamine receptor 1A; 5-hydroxytryptamine (serotonin) receptor 1A; ADRB2RL1; ADRB2RL15HT1a; ADRBRL1; G protein coupled receptor; G-21; guanine nucleotide-binding regulatory protein-coupled receptor; HTR1A; PFMCD; Serotonin receptor 1A

Molecular Weight

Mass (kDA):
46.107 kDA

Genomic Context


Human

Location:	5q12.3
Sequence:	5; NC_000005.10 (63957874..63962445, complement)

Tissue Specificity

Detected in lymph nodes, thymus and spleen. Detected in activated T-cells, but not in resting T-cells.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Depressive Disorder
Major Depressive Disorder
Anxiety Disorders
Mental Disorders
Cancer Patients And Suicide And Depression
Stress, Psychological
Dysequilibrium Syndrome
Schizophrenia
Mood Disorders
Nervousness
Cholangiocarcinoma

Bipolar Disorder
Depressive Symptom
Panic Disorder
Malnutrition
Personality Disorders

Interacting Proteins

FGFR1
GALR1
GPR39
HTR2A

Pathways

Pathogenesis
Transport
Response To Fluoxetine
Response To Antidepressant
Response To Stress
Brain Development
Neurogenesis
Oxidative Phosphorylation
Reflex
Swimming
Thigmotaxis
Response To Clozapine

Translation
Cognition
Dna Methylation
Metaphase
Localization
Methylation
Regeneration

PTMs

Phosphorylation

Methylation

Research Areas

Cell Cycle and Replication
GPCR

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HTR1A

References

PMID: 3041227 by Kobilka B.K., et al. An intronless gene encoding a potential member of the family of receptors coupled to guanine nucleotide regulatory proteins.

PMID: 15014171 by Kitano T., et al. Human-specific amino acid changes found in 103 protein-coding genes.